Description
Covering pertinent basic science and offering today's most authoritative guidance on clinical management, Fetal Medicine, 3rd Edition, is a must-have resource for obstetricians and other healthcare professionals involved in care of the fetus. An international team of expert contributors delivers the knowledge and background you need to effectively diagnose and treat fetal disorders – everything from prenatal screening and diagnostic tests to common and rare prenatal conditions, early pregnancy loss, ethical issues, and much more.- Focuses on fetal medicine throughout, bringing you today's most reliable information in both basic science and clinical topics.- Offers updated information from cover to cover, including new coverage of genetics, embryology, and clinical management.- Features new self-assessment questions and new images throughout – for a total of nearly 1,000 photographs and line drawings, as well as more than 150 quick-reference tables.- Details fast-changing developments in fetal medicine, including advances in ultrasound imaging, cytogenetics, molecular biology, and biochemistry.- Helps you learn and retrieve complex information quickly thanks to succinct, highly structured text; key points at the beginning of each chapter; and concise chapter summaries.New editor team – 3 new editors with an international approach – they will select qualified authors who can discuss the basic science as well as the clinical aspects of perinatal problemsUpdated knowledge content – major areas of change are non-invasive prenatal testing (NIPT) and genetic testing – Ron Wapner is one of the leaders in these fieldsExpert Consult access – individual electronic access for the first time4-color design – current design is b&w so will update with new colors and colorize the drawings.
Table of Contents
Section 1: Early Fetal Development1 Early Concepts and Terminology, 2Patricia Collins2 Cellular Mechanisms and Embryonic Tissues, 6Patricia Collins3 Staging Embryos in Development and theEmbryonic Body Plan, 23Patricia Collins4 Teratology, 30Sarah G. Obican and Anthony R. Scialli5 Early Pregnancy Failure, 38Davor Jurkovic and Kuhan RajahSection 2: The Placenta6 The Immunology of Implantation, 48Ashley Moffett, Y.W. Loke and Andrew Sharkey7 Development of the Placenta and ItsCirculation, 55Caroline E. Dunk, Berthold Huppertz and John C. Kingdom8 Placental Function in MaternofetalExchange, 69Colin Sibley and Mark Dilworth9 Placental Pathology and Implications for FetalMedicine, 78Neil J. Sebire and John C. KingdomSection 3: Fetal Physiology and Pathology10 Development of the Heart and CardiovascularSystem in Relation to Cardiac Abnormalities, 88Michael Ashworth11 Lung Growth and Maturation, 103Richard Harding, Annie R.A. McDougall and Stuart B. Hooper12 Development of the Kidneys and Urinary Tract inRelation to Renal Anomalies, 114Paul J.D. Winyard13 The Perinatal Postmortem Examination, 121J. Ciaran Hutchinson, Susan C. Shelmerdine and Neil J. SebireSection 4: Epidemiology14 Epidemiologic and Research Methods in FetalMedicine, 132Cande V. Ananth and Alan T. TitaSection 5: Ethics15 Ethical Issues in Maternal-Fetal Medicine, 139Wybo J. Dondorp and Guido M. de WertSection 6: Prenatal Screening and Diagnosis16 Principles of Screening, 149Joshua I. Rosenbloom and George A. Macones17 Conveying Information About Screening andDiagnosis, 154Jenny Hewison, Louise D. Bryant and Jane Fisher18 Ultrasound and Biochemical Screening for FetalAneuploidy, 161Howard Cuckle and Ran Neiger19 Ultrasound Screening for Fetal Abnormalities inthe First Trimester, 176Caterina M. Bilardo and Frederick Ushakov20 Evidence for Routine Ultrasound Screening forFetalAbnormalities in the Second and ThirdTrimesters,194Yalda Afshar, Rashmi Rao, Anahit Martirosian andLawrence D. Platt21 Noninvasive Screening for Cytogenetic Disorders(Fetal Aneuploidy Including Microdeletions), 202Karen Wou and Ronald J. Wapner22 Noninvasive Prenatal Diagnosis for Single-GeneDisorders, 214Melissa Hill and Lyn S. ChittyContentsContents vii23 Invasive Diagnostic Procedures, 225Anthony O. Odibo and Ganesh Acharya24 Prenatal Diagnosis of ChromosomeAbnormalities, 233Colleen G. Bilancia, Mythily Ganapathi and Brynn Levy25 Advances in Molecular Genetics Including FetalSequencing, 247Magdalena Walkiewicz and Ignatia B. Van den Veyver26 Expanded Carrier Screening, 254Liran Hiersch and Yuval Yaron27 Prenatal Screening for Thalassemias, 263Kwok Yin Leung, Patrick Au and Mary TangSection 7: Diagnosis and Management ofFetal Malformations28 Sonography of the Fetal Central NervousSystem, 275Luc De Catte, Bart De Keersmaecker, Luc Joyeux andMichael Aertsen29 The Heart, 305Christoph Wohlmuth and Helena M. Gardiner30 Fetal Lung Lesions, 324James Cook, Angela Yulia, Colin Wallis and Pranav P. Pandya31 Congenital Diaphragmatic Hernia, 332Francesca Maria Russo, Liesbeth Lewi, Jute Richter andJan Deprest32 Abdomen, 340Jon Hyett33 Kidney and Urinary Tract Disorders, 351Roland Devlieger and An Hindryckx34 Diagnosis and Management of Fetal SkeletalAbnormalities,373Lyn S. Chitty, Louise C. Wilson and Frederick Ushakov35 Diagnosis and Management of Abnormalities ofthe Face, 402Elisabeth de Jong-Pleij and Caterina M. Bilardo36 Fetal Hydrops, 427Sylvie Langlois and R. Douglas Wilson37 Fetal Tumours, 443Thomas R. Everett, Rosalind Pratt, Colin R. Butler, Richard J.Hewitt, Paolo De Coppi and Pranav P. Pandya38 Open Fetal Surgery, 454Luc Joyeux, Frank Van Calenbergh, Roland Devlieger,Luc De Catte and Jan DeprestSection 8: Diagnosis and Management ofOther Fetal Conditions39 Fetal Growth and Growth Restriction, 469Emily J. Su and Henry L.
