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Full Description
The book entitled "Exploring the Synthesis, Ethnopharmacology, and Therapeutic Applications of Bioactive Polyphenols" offers a comprehensive examination of one of the most dynamic areas in natural product chemistry and drug discovery. Polyphenols, long recognized for their diverse biological activities, are now at the forefront of research in preventive medicine, nutraceuticals, and pharmaceutical innovation. This book brings together the chemistry, traditional uses, and modern therapeutic perspectives of bioactive polyphenols in a single, well-structured volume.
The aim of this book is to bridge the gap between traditional ethnopharmacological knowledge and cutting-edge synthetic and therapeutic research. By integrating interdisciplinary perspectives, it provides a unique resource for understanding both the molecular intricacies of polyphenols and their real-world applications in treating chronic diseases. What sets this work apart is its balanced approach offering in-depth scientific analysis while also capturing the cultural and historical significance of these bioactive compounds.
Key Features:
Detailed coverage of the chemical synthesis and structural diversity of major polyphenols.
Comprehensive insights into ethnopharmacological practices involving polyphenol-rich plants across different cultures.
Thorough discussion of therapeutic applications, including cardiovascular, neuroprotective, anticancer, and anti-inflammatory potentials.
Integration of recent advances in clinical studies and drug formulation strategies.
New to this edition: expanded chapters on nanotechnology-based delivery systems, sustainability in polyphenol extraction, and updated case studies highlighting translational research.
This volume is an essential reference for researchers, academicians, and graduate students in pharmaceutical sciences, medicinal chemistry, pharmacognosy, and natural product research. It will also be invaluable to healthcare professionals, nutritionists, and industry specialists seeking to explore the therapeutic promise of polyphenols and their role in future drug discovery.
Contents
1. Introduction to Bioactive Polyphenols 2. Synthetic Strategies for Bioactive Polyphenols 3. Synthesis of Phenolic Acid and Flavanoids 4. Total Synthesis of Resveratrol and Stilbenes 5. Synthesis of Lignans and Lignan Glycosides 6. Chemical Modifications of Polyphenols 7. Synthesis of Polyphenol Conjugate and Prodrugs 8. Bioactive Polyphenols in Drug Discovery 9. Applications of Synthetic Bioactive Polyphenols 10. Future directions in Polyphenol synthesis for the treatment of Neuropathic Pain 11. Enzymatic Approaches in Polyphenol Synthesis 12. Multicomponent Reaction for Polyphenol Synthesis 13. Sustainable Synthesis of Bioactive Polyphenols 14. Advances in Polyphenol Modification and Functionalization 15. Nanotechnology for Polyphenol Delivery and Applications 16. Enhancing Polyphenol Bioavailability: Cutting-Edge Advances and Strategies 17. Synthetic Polyphenols for Neurodegenerative Diseases 18. Polyphenols in Functional Materials and Biotechnology 19. Challenges and Opportunities in Polyphenol Synthesis
