Description
Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases.- Includes design, synthesis and applications of drug delivery systems- Explores the role of nanotechnology in the diagnosis and treatment of neurodegenerative disorders- Reviews applications for the management of Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases- Discusses extracellular vesicles and mitochondria-targeted bioactive delivery systems- Details how nanocarrier-based delivery is useful to improve efficacy and cure
Table of Contents
1. Aetiology and pathophysiology of neurodegenerative disordersRakesh K. Sahoo, Tanisha Gupta, Smilly, Vinay Kumar, Sarita Rani, and Umesh Gupta2. Targeted nanoparticles for the treatment of Alzheimer's diseaseDavood Gheidari and Mohammad Bayat3. Neurodegenerative disorders due to inhalation of various small particlesKrishna Jadhav, Raghuraj, Eupa Ray, Kalpesh Vaghasiya, and Rahul Kumar Verma4. Lipid nanocarrier-based drug delivery for the treatment of brain-related disordersSatish Shilpi, Ashish Jain, Sonal Dixit, Gaurav Saraogi, Awesh Kumar Yadav, and Sanjay K. Jain5. Nanomedical drug delivery for neurodegenerative diseaseNavjot Kaur, Vanktesh Kumar, Thatikayala Mahender, Indrani Maji, Shrusti Mahajan, Pankaj Kumar Singh, and Sanjeev Kumar Sahu6. siRNA polymer conjugates for the delivery of RNAi therapeutics for the treatment of Parkinson's diseasePriya Singh, Nidhi Mishra, Neelu Singh, Alka Sonkar, Samipta Singh, Raquibun Nisha, Priyanka Maurya, Ravi Raj Pal, and Shubhini A. Saraf7. Potential of nanoparticles as novel therapeutics against Alzheimer's DiseaseRewati Raman Ujjwal, Sandeep Kr Maharana, Mayank Handa, and S.T.V. Sai Krishna8. Recent trends of extracellular vesticles for therapeutic intervention of brain-related diseasesMayank Handa, Reddy Gayathri Aparnasai, Nikita Panicker, Sanjiv Singh, and Munindra Ruwali9. Mitochondria-targeted drug delivery systems for the effective treatment of neurodegenerative disordersVaishali Khare, Surbhi Gupta, Preeti Bisht, and Debapriya Garabadu10. Recent trends of theranostic applications of nanoparticles in neurodegenerative disordersSarjana Raikwar and Sanjay K. Jain11. Role of nanoparticles in neurotoxicityRishi Paliwal, Kunjbihari Sulakhiya, Shivani Rai Paliwal, Vijal Singh, Rameshroo Kenwat, and Debashish Paramanik12. Metal nanoparticles for neurodegenerative diseasesShagufta Haque and Chitta Ranjan Patra13. Nano-based phytodrug delivery systems for the management of neurodegenerative disordersM.S. Sudheesh and R.S. Pawar14. Nanoparticle-mediated delivery of AChE inhibitors for the treatment of Alzheimer's diseasePallav Namdeo, Jinu Mathew, and Ashish Garg15. Nanomaterial-bsed drug delivery systems as tools for targeted therapy of neurodegenerative diseasesRahul Shukla, Vaibhavi Srivastava, Aakriti Sethi, and Munindra Ruwali16. Sample preparation techniques for quantitative analysis in brain pharmacokinetics: Application to neurodegenerative diseasesPramod Kumar, Waibiangki Lyngdoh, Banwarilal, and Amit Alexander
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