Non-Hodgkin's Lymphoma in Childhood and Adolescence〈1st ed. 2019〉

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Non-Hodgkin's Lymphoma in Childhood and Adolescence〈1st ed. 2019〉

  • 言語：ENG
  • ISBN：9783030117689
  • eISBN：9783030117696

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Description

This text provides a state-of-the-art overview on Non-Hodgkin's lymphoma (NHL) in children and adolescents. The volume is divided into seven sections, each of which focuses on a critical component of pediatric NHL, including history and epidemiology, pathology and molecular biology, disease evaluation and response, common and rare sub-types of NHL, and current and novel treatment strategies. The text also comprehensively reviews the late effects of treatment, quality of patient life, and NHL treatment in countries with limited resources.

Written by experts in the field, Non-Hodgkin's Lymphoma in Childhood and Adolescence is a valuable resource for clinicians and practitioners who treat children and adolescents with NHL.

Table of Contents

Part I. Introduction

1. History of Diagnoses and Treatment Strategies in Pediatric Non-Hodgkin's Lymphomas
Georg Mann

2. Epidemiology of Non-Hodgkin Lymphomas in Childhood and Adolescence
Nirav Thacker, Oussama Abla 

3. Diagnosis and Classification
Thierry Jo Molina


Part II. Pathology and Molecular Biology

4. Pathogenesis of B-cell Lymphoma 
Rabea Wagener, Cristina López, Reiner Siebert 

5. Pathogenesis of T-Non-Hodgkin’s Lymphoma
Jonathan Bond, Owen Patrick Smith

6. The Pathogenesis of Anaplastic Large Cell Lymphoma
Suzanne Dawn Turner

7. Pathology
Christoph Kornauth, Ana-Iris Schiefer, Ingrid Simonitsch-Klupp

8. Genetic Predisposition to Non-Hodgkin Lymphoma
Oskar A. Haas, Arndt Borkhardt


Part III. Evaluation

9. Response Assessment in Pediatric Non-Hodgkin Lymphoma
Tony H. Truong, Veronique Minard-Colin

10. Minimal Disseminated and Minimal Residual Disease in Pediatric Non-Hodgkin Lymphoma
Lara Mussolin, Christine Damm-Welk, Wilhelm Woessmann

11. Prognostic Factors in Childhood and Adolescent Non-Hodgkin Lymphoma
Marta Pillon, Ana C. Xavier, Mitchell S. Cairo


Part IV. Lymphoblastic lymphoma

12. Lymphoblastic Lymphoma
Birgit Burkhardt, Birte Wistinghausen 


Part V. Mature B- Non-Hodgkin’s lymphomas

13. Burkitt’s Lymphoma and Diffuse Large B-cell Lymphoma
Grace Egan, Sheila Weitzman, Sarah Alexander

14. Primary Mediastinal and Gray Zone Lymphomas
Lisa Giulino-Roth, Kieron Dunleavy

15. Epstein-Barr Virus-associated Post-transplantation Lymphoproliferative Disease
Ashely V. Geerlinks, Thomas G. Gross, Angela S. Punnett

16. Pediatric-Type Follicular Lymphoma (PTFL)
Andishe Attarbaschi

17. Marginal Zone Lymphoma
Birgit Burkhardt

18. Primary Central Nervous System Lymphoma (PCNSL)
Oussama Abla, Tracy T. Batchelor, Andishe Attarbaschi

19. Rare B-cell non-Hodgkin’s Lymphomas (B-NHL) in Childhood and Adolescence
Auke Beishuizen, Vasiliki Tzotzola, Lena Uzunova, Amos Burke


Part VI. Mature T- Non-Hodgkin’s lymphomas

20. Anaplastic Large Cell Lymphoma in Children and Adolescents
Eric J. Lowe, Laurence Brugieres 

21. Peripheral T-cell Lymphoma
Karin Mellgren, Udo Kontny

22. Extranodal NK/T cell lymphomas and EBV+ Lymphoproliferative Diseases of Childhood
Chinadol Wanitpongpun, Ritsuro Suzuki

23. Cutaneous T-cell Lymphomas in Childhood and Adolescence
Rein Willemze


Part VII. Treatment

24. Principles of Immunotherapy
Stanton Goldman, Jessica Hochberg

25. Hematopoietic Stem Cell Transplantation
Tetsuya Mori, Tomoo Osumi

26. Novel Therapies in Pediatric NHL
Amos Burke, Joerg Krueger, Birte Wistinghausen

27. Childhood and Adolescence Non-Hodgkin Lymphomas in Low- and Middle-Income Countries
Nmazuo W. Ozuah, Nader Kim El-Mallawany

28. Long-Term Outcomes in Survivors of Childhood and Adolescent Non-Hodgkin Lymphoma
Karin Langenberg, Noelle Cullinan, Paul C. Nathan