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Description
A multi-authored and comprehensive text, Cell Physiology Source Book enables graduate students in various biological sub-disciplines to gain a thorough understanding of cell physiology. It begins with a reviewof the physical chemistry of solutions, protein structure, and membrane structure, and ends with an Appendix featuring reviews of electricity, electrochemistry, and cable properties of cells. In between, this book is loaded with information on membrane potentials, cell metabolism, signal transduction, transport physiology and pumps, membrane excitability and ion channels, synaptic transmission, sensory transduction, muscle contraction, excitation-contraction coupling, bioluminescence, photosynthesis, andplant cell physiology.This exhaustive work provides graduate students with detailed and authoritative coverage of nearly all aspects of cell physiology. Such broad coverage of this field within a single source makes for a unique text.Chapters written in a clear, concise, and didactic style, and appropriate reviews of basic physics and chemistry are among the many distinguishing features of this monumental treatise.Comprehensive source-book of cell physiologyAuthoritative and multi-authored by leading experts in the fieldUnique features include broad coverage and review of relevant physics, chemistry, and metabolismClear, concise, and didacticIncludes reviews of physical chemistry of solutions, protein structure, membrane structure, electrochemistry, and electricityTopic covered include plant cell physiology, photosynthesis, bioluminescence, effects of pressure, cilia, and flagellaeDetailed treatise on ion channels and their regulation
Table of Contents
Biophysical Chemistry, Electrochemistry, Metabolism, Second Messengers, and Ultrastructure: J.C. Freedman, Biophysical Chemistry of Cellular Electrocytes. M.R. Pincus, The Physiological Structure and Functionof Proteins. F. Schroeder and W.G. Wood, Lateral Lipid Domains and Membrane Functions. D.G. Ferguson, Ultrastructure of Cells. N. Sperelakis, Diffusion and Permeability. N. Sperelakis, Origin of Resting Membrane Potentials. N. Sperelakis, GibbsDonnan Equilibrium Potentials. M.A. Lieberman and R.G. Sleight, Energy Production and Metabolism. R.G. Sleight and M.A. Lieberman, Signal Transduction. J.R. Dedman and M.A. Kaetzel, Calcium as an Intracellular Second Messenger: Mediated by Calcium Binding Proteins. Transport Physiology, Pumps, and Exchangers: J. Cuppoletti, Transport of Ions and Non-Electrolytes. E.T. Wallick, The Sodium Pump. I. Edes and E.G. Kranias, Ca2+-ATPases.J.H.B. Bridge, NaCa Exchange Currents. C.M. Baumgarten and J.J. Feher, Osmosis and Regulation of Cell Volume. R.W. Putnam, Intracellular pH Regulation. R.W. Putnam, Polarity of Cell Membranes. Membrane Excitability and IonChannels: N. Sperelakis, Cable Properties and Propagation of Action Potentials. N. Sperelakis, Electrogenesis of Membrane Excitability. RY.K. Pun and H. Lecar, Patch-Clamp Techniques and Analysis. S.R. Levinson, Structure and Mechanism of Voltage-Gated Ion Channels. B. Nilius, Ion Channels in Nonexcitable Cells. A. Lievano and A. Darszon, Ion Channels in Sperm. W.J. Larsen and E.M. Hendrix, Biology of Gap Junctions. L.J. DeFelice and M. Mazzanti, Biophysics of the Nuclear Envelope.N. Sperelakis, Regulation of Ion Channels by Phosphorylation. A. Yatani, Ion Channels that are Directly Regulated by G Proteins. Ion Channels as Targets for Toxins, Drugs, and Diseases: K. Blumenthal, Ion Channels as Targets for Toxins. R.K. Hermsmeyer, Ion Channels as Targets for Drugs. S.H. Bryant, Ion Channels as Targets for Genetic Disease. Synaptic Transmission and Sensory Transduction: G.L. Westbrook, Ligand-Gated Ion Channels. J.B. Suszkiw, Synaptic Transmission. N. Gallo-Payet and M.D. Payet, ExcitationSecretion Coupling. C.E. Morris, Stretch-Sensitive Ion Channels. M.M. Behbehani, Mechanoreceptor and Sonoreceptor Transduction. A.L. Zimmerman, Cyclic Nucleotide-Gated Ion Channels. A.L. Zimmerman, Visual Transduction. S. Roper, Olfactory/Taste Receptor Transduction. S. Misler, Stimulus Transduction in Metabolic Sensor Cells. Muscle and Other Contractile Systems: N. Sperelakis, Skeletal Muscle Action Potentials. G.M. Wahler, Cardiac Action Potentials. R.K. Hermsmeyer, Smooth Muscle Action Potentials. G. Meissner, Ca2+ Release from Sarcoplasmic Reticulum in Muscle. R.J. Paul, Contractility of Muscles. E.S. Kaneshiro, Amoeboid Movement, Cilia, and Flagella. E.S. Kaneshiro, Spasmonemes/Centrin-Based Contraction and Bacterial Flagella. T.K. Akers, Physiological Effects of Pressure on Cell Function. Bioluminescenceand Photosynthesis: J.W. Hastings, Bioluminescence. D. Fleischman, Photosynthesis. R.G. Stout, Plant Cell Physiology. Appendix Section: N. Sperelakis, Review of Electricity and Cable Properties. Subject Index.
