Full Description
Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell-based techniques is that current therapies lack controlled environments that are crucial for regulating stem cell engraftment and differentiation in vivo, because stem cells are rather sensitive to even minute changes in their environment. Micro- and nanotechnology hold great potential to fabricate biomimetic spatiotemporally controlled scaffolds as well as control stem cell behavior and fate by micro- and nanoscale cues.
This book presents the latest micro- and nanotechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. Moreover, it covers and details cutting-edge research in nano- and microfabrication techniques and biomaterials for the regeneration of various tissues and organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, cardiac, and vascular tissues.
Contents
Nano and Microtechnology. Nano/Microfibrication Techniques for Tissue and Organ Regeneratio. Three Dimensional Micropatterning of Biomaterial Scaffolds for Tissue Engineering. Nanobiotechnology and Biomaterials for Regenerative Medicine. Micro- and Nanotechnology Engineering Strategies for Tissue Interface Regeneration and Repair. Spatiotemporal Genetic Control of Cellular Systems. Biomimetic Design of Extracellular Matrix-like Substrate for Tissue Regeneration. Degradable Elastomers for Tissue Regeneration. Protein Engineering Strategies for Modular, Responsive, and Spatially Organized Biomaterials. Tissue and Organ Regeneration. Design and Fabrication of Biomimetic Microvascular Architecture. The Self-Assembly Process of Articular Cartilage and Self-Organization in Tissue Engineering. Environmental Factors in Cartilage Tissue Engineering. Bone Regenerative Engineering: The Influence of Micro and Nano Dimension. Stem Cell and Bone Regeneration. Notch Signaling Biomaterials and Craniofacial Regeneration. Stem Cell-Based Dental, Oral and Craniofacial Tissue Engineering. Engineering Functional Bone Grafts for Craniofacial Regeneration. Nanotechnology in Osteochondral Regeneration. Aortic Heart Valve Tissue Regeneration. Micro and Nanotechnology in Vascular Regeneration. Micro- and Nanofabrication Approaches to Cardiac Tissue Engineering. Engineering of Skeletal Muscle Regeneration: Principles, Current State and Challenges.
