- ホーム
- > 洋書
- > ドイツ書
- > Mathematics, Sciences & Technology
- > Chemistry
Description
(Text)
This book is unique with a complete coverage of the developments in the last 10 years by experts in the field with up-to-date information and maintaining continuity to the previous book that appeared in 2013. It presents main advances that inspired chemists in the last decade of a large segment of organic chemistry in a nutshell. The book is the continuation of the Comprehensive Enantioselective Organocatalysis. Consequently, it retains the main features of its predecessor, with two notable differences: (i) a larger number of conscise chapters are covered with developments in a rapidly expanding field, (ii) Experimental procedures are not presented, as most of them are similar to those already discussed in the previous edition.
(Table of content)
Privileged Catalysts Structures in Organocatalytic Reactions
Basicities and Nucleophilicities of N-Centered Organocatalysts
Aldol, Mannich and Associated Hetero-Diels-Alder Reactions and Conjugate Addition Reactions
Aminocatalysis-2 Reactions with nitrogen-centered 1,3-dipoles
Aminocatalysis-3 Selected examples of aminocatalytic direct alpha-heteroatom functionalization and direct alpha-alkylation
Aminocatalysis-4 Chiral Imidazolidinone (MacMillan?s) Catalyst
Enantioselective Carbonyl Catalysis
Non-classical hydrogen bond (NCHB) interactions in Enantioselective Organocatalysis
Progress in (Thio)urea- and Squaramide-Based Brønsted Acid and Brønsted Base Catalysts
Strong Brønsted Acids
Brønsted bases
N-Heterocyclic Carbenes in Asymmetric Organocatalysis: Methods and Applications
Non-Covalent Activations - Lewis Acids
Organocatalytic transformations with chiral phosphines
Lewis-Base Asymmetric Organocatalysis for Enantioselective Construction of C-O and C-N bonds
Synthetic transformations assisted by halogen, chalcogen, and pnictogen bonding
Activation Modes in Asymmetric Anion-Binding Catalysis
Transformations with chiral phase-transfer catalysts
Synthetic Peptide Mediated Asymmetric Organocatalysis
Carbohydrates-A Promising Moiety for Organocatalysis
Chiral Polymer Catalysts
Combined Power of Organo- and Transition Metal Catalysis in Enantioselective Organic Synthesis
Emerging Organocatalyst Classes from Renewable Sources
Catalysts recovery strategies (Polymer and Mesoporous Material Supported
Catalyst design within asymmetric organocatalysis
A Critical Overview on Catalysts Synthesis
Organocatalytic Oxidations
Asymmetric organocatalytic conjugate additions
Recent Advances in Asymmetric Organocatalytic Inert C-H Bond Functionalization
Enantioselective Multicatalyzed Multistep Reactions
Combining Organocatalysis and Biocatalysis in One-Pot Procedures
Light-controlled organocatalysis by bifunctional single-catalyst systems
Dual photo/organocatalytic strategies in asymmetric synthesis
Miscellaneous Organocatalytic Redox and Electron Transfer Reactions
Enantioselective Synthesis Enabled by Electrochemistry
Asymmetric Organocatalysis in Water, Water in Asymmetric Organocatalysis
Chiral Ionic Liquids and Deep Eutectic Solvents
Strategies towards Asymmetric Organocatalysis at Parts-per-Million Loadings
Diastereo- and enantiodivergent synthesis with organocatalysis
Site-selective organocatalytic transformations and remote functionalisations
Organocatalytic Dynamic Kinetic Resolution
Organocatalysis in carbohydrate synthesis
Organocatalysis in Polymer Science
Asymmetric organocatalysis in medicinal chemistry
Asymmetric Organocatalysis in Drug Discovery and the Patent Literature
(Author portrait)
Peter I. Dalko (1960) completed his graduate studies at the Technical University of Budapest (BME), and earned his PhD at Paris XI, France under the supervision of Stéphane D. Gero. After a post-doctoral internship with Derek H. R. Barton (Texas A & M University, USA), and Yoshito Kishi (Harvard University, USA) he is working at the Paris Cité University, France, (CNRS). His group is focusing on the development of enantiocatalytic reactions for organic synthesis, the design and application of light-sensitive molecular probes allowing accurate 4-dimensional control of biological events in complex tissues, and on the preparation of remotely controllable drug delivery systems with imaging ability.
Contents
1. AMINOCATALYSIS
1.1 Explaining Anomalies in Enamine Catalysis: "Downstream Species" as a New Paradigm for Stereocontrol
1.2 Synergistic Strategies in Aminocatalysis
1.3 New trends in amino Acid-derived and Peptides Organocatalysts
1.4 Recent advances in amine catalyzed organocatalytic transformations
2. ENANTIOSELECTIVE CARBONYL CATALYSIS ENABLED BY CHIRAL ALDEHYDES
3. HYDROGEN-BOND DONOR CATALYSIS
3.1 Non-Classical C-H center dot center dot center dot X Hydrogen Bonding and Its Role in Asymmetric Organocatalysis
3.2 Chiral guanidines and thiourea derivatives in asymmetric synthesis
3.3 Squaramide-Catalyzed Asymmetric Reactions
3.4 Recent advances in asymmetric reactions catalyzed by chiral phosphoric acids
3.5 Dual Bronsted-acid Organocatalysis: Cooperative Asymmetric Catalysis with Combined Phosphoric and Carboxylic Acids
3.6 Brønsted acid catalysts and ?silylium? Lewis acid precatalysts Imidodiphosphorimidates (IDPis)
3.7 Stronger Bronsted Acids: Recent Progress (Akiyama, T and Mori, K)
4. PHOSPHINE ORGANOCATALYSIS
5. ION-PAIRING CATALYSIS
5.1 Activation Modes in Asymmetric Anion-Binding Catalysis
5.2 Asymmetric counteranion-directed catalysis (ACDC)
5.3 Phosphonium Salts in Asymmetric Catalysis: A Journey in a Decade's Extensive Research Work
5.4 Recent Progress in Asymmetric Ion-Pairing Catalysis with Ammonium Salts
6. PHASE-TRANSFER CATALYSTS
6.1 Design of high-performance chiral phase-transfer catalysts with privileged structures
6.2 Assisted by Hydrogen-Bond Donors: Cinchona Quaternary Salts as Privileged Chiral Catalysts for Phase-Transfer Reactions
6.3 Phase-Transfer and Ion-Pairing Catalysis of Pentanidiums and Bisguanidiniums
7. HALOGEN, CHALCOGEN
7.1 Halogen, Chalcogen, Anion-pi Bonding and sigma-Hole Interactions in Catalysis
7.2 Halogen Bonding in Organic Synthesis and Organocatalysis
7.3 Chalcogen Bonding: An Overview
8. SULFUR YLIDES
9. CHIRAL HYPERVALENT IODINES: ACTIVE PLAYERS IN ASYMMETRIC SYNTHESIS.
10. LEWIS BASE CATALYSIS PROMOTED NUCLEOPHILIC SUBSTITUTIONS -
RECENT ADVANCES AND FUTURE DIRECTIONS
11. ACTIVATING PRONUCLEOPHILES WITH HIGH PK(A) VALUES: CHIRAL ORGANO-SUPERBASES
12. RECENT ADVANCES IN THE CHEMISTRY AND APPLICATIONS OF N-HETEROCYCLIC CARBENES
13. ENANTIOSELECTIVE REDOX AND RADICAL REACTIONS IN THE DARK BY CHIRAL CATALYSTS
14. ORGANOCATALYSIS IN INERT C-H BOND FUNCTIONALIZATION
15. ENANTIOSELECTIVE DESYMMETRIZATION REACTIONS IN ASYMMETRIC CATALYSIS
16. TWO AND MORE CATALYSTS SYSTEMS
16.1 Two and Multi-organocatalyst Systems
16.2 Combined Power of Organo- and Transition Metal Catalysis in Organic Synthesis
16.3 Asymmetric Reactions Enabled by Cooperative Enantioselective Amino- and Lewis Acid Catalysis
16.4 Organocatalysis and Biocatalysis Hand in Hand: Combining Catalysts in One-Pot Procedures
17. RECENT PROGRESS IN ORGANOCATALYTIC ASYMMETRIC DOMINO TRANSFORMATIONS
18. MULTICOMPONENT AND MULTICATALYTIC REACTIONS -
A SYNTHETIC STRATEGY INSPIRED BY NATURE
19. STEREODIVERGENT ASYMMETRIC SYNTHESIS VIA ORGANOCATALYSIS
20. CATALYSTS RECOVERY STRATEGIES:
20.1 Fluorous organocatalysis
20.2 Covalently Supported Ionic Liquid Phases: An Advanced Class of Recyclable Catalytic Systems
20.3 Polymer Supported organocatalysts
21. SUPRAMOLECULAR CATALYSIS
21.1 Harnessing DNA as a Designable Scaffold for Asymmetric Catalysis: Recent Advances and Future Perspectives
21.2 Chitosan Based Catalyst and Their Mode of Action
21.3 Functionalized Macrocycles in Supramolecular Organocatalysis .
21.4 Nanopores of a Covalent Organic Framework: A Customizable Vessel for Organocatalysis
21.5 Asymmetric Catalysis Under 1D/2D Nanostructured Materials
21.6 Synthesis of Chiral Polymer Catalysts and Their Application to Asymmetric Reactions
21.7 Stable, crystalline, porous, covalent organic frameworks as a platform for chiral organocatalysts
21.7 Enabling protein-hosted organocatalytic transformations
22. SITE SELECTIVE AND REMOTE FUNCTIONALIZATION:
22.1 Recent advances in site-selective functionalization of carbohydrates mediated by organocatalysts
22.2 N-Heterocyclic Carbene Catalysis via Azolium Dienolates: An Efficient Strategy for Remote Enantioselective Functionalizations
22.3 Advances in Organocatalytic 1,6-Addition Reactions: Enantioselective Construction of Remote Stereogenic Centers
22.4 Site-selective reactions mediated by molecular containers
23. NON-CONVENTIONAL ACTIVATION METHODS:
23.1 Mechanochemical Organocatalysis: Do High Enantioselectivities Contradict What We Might Expect?
23.2 Microwave-assisted Organo-catalyzed C-C and C-X (Heteroatom) Bond-forming Reactions
23.3 Modern Electrochemical Aspects for the Synthesis of Value-Added Organic Products
24. ORGANOCATALYSIS IN NON-CONVENTIONNAL MEDIAS
24.1 Organocatalysis in aqueous media
24.2 Chiral Ionic Liquids and Deep Eutectic Solvents in Asymmetric Synthesis
24.3 Application of Biobased Solvents in Asymmetric Catalysis (
25. LIGHT IN ORGANOCATALYSIS
25.1 Recent Trends in Photocatalytic Enantioselective Reactions
25.2 Organophotoredox catalysis : reactions and Structure-Property Relationships of catalysts
25.3 Photoredox Dual Catalysis
26. SWITCHABLE CATALYSTS : DYNAMIC RESPONSIVE SYSTEMS FOR CATALYTIC FUNCTION
27. EMERGING SYSTEMS:
27.1 Bio-Inspired Quinone Catalysis
27.2 Taurine: A Water Friendly Organocatalyst in Organic Reactions
27.3 Vitamin B1: A Versatile Organocatalyst for Organic Synthesis
27.4 Growing Impact of Carbohydrate-Based Organocatalysts
28. COMPUTATIONAL INSIGHTS
28.1 The Central Role of Nonbonding Interactions in Modern Covalent Organocatalysis
28.2 Transition State Models for Understanding the Origin of Chiral Induction in Asymmetric Catalysis
28.3 Catalyst Design Within Asymmetric Organocatalysis (
29. APPLIED ORGANOCATALYSIS:
29.1 Low-loading asymmetric organocatalysis
29.2 Asymmetric organocatalysis: an enabling technology for medicinal chemistry
29.3 New chemical processes to streamline carbohydrate synthesis
29.4 Organocatalytic Asymmetric Methodologies towards the Synthesis of Atropisomeric N-Heterocycles
29.5 Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters
29.6 Organocatalyzed Asymmetric Synthesis of Axially, Planar, and Helical Chiral Compounds
29.7 Recent Advances in Organocatalytic Kinetic Resolution for the Synthesis of Functionalized Products
29.8 Recent applications of asymmetric organocatalytic annulation reactions in natural product synthesis
29.9 Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions
29.10 Synthesis of Cyclic Fragrances
29.11 Organocatalytic Atroposelective Synthesis of N-N Axially Chiral Indoles and Pyrroles by De Novo Ring Formation
29.12 Macromolecular architectures through organocatalysis
29.13 Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products
29.14 Asymmetric Organocatalytic Tandem/Domino Reactions to Access Bioactive Products
29.15 Synthesis of radio isotope labelled products with organocatalysis
30. VALORIZATION OF WASTE: SUSTAINABLE ORGANOCATALYSTS FROM RENEWABLE RESOURCES
31. HIGHLIGHTS OF THE RECENT PATENT LITERATURE: FOCUS ON ASYMMETRIC ORGANOCATALYSIS
