Full Description
Antimicrobial resistance (AMR) is one of the deadliest threats to global public health. This book focuses on dynamics in the landscape of AMR while informing about the latest technologies and strategies to mitigate it. The menace of AMR in different niches, routes of penetration across various domains, socio-economic impact, and the need for a 'One Health' approach in mitigating AMR has been emphasized. Factors involved in AMR, underlying mechanisms, and pharmacometrics in developing antimicrobials are highlighted. Emphasis is given to emerging technologies that are sustainable, scalable, and applicable to the global community, such as big data analytics, bioactive agents, phage therapy, and nanotechnology. The book also explores current and alternative treatment strategies to combat AMR, emphasizing the use of nanoparticles to target pathogens and as a viable alternative to antibiotics.
Contents
1. Antimicrobials in livestock production and its cross-domain dynamics.- 2. Antibiotics and resistance in environment.- 3. Antimicrobials in agriculture and its implications in antimicrobial resistance.- 4. Modern diagnostic tools for rapid detection of multidrug resistance.- 5. The use of antimicrobials in agriculture and socio-economic considerations in a global world.- 6. Epidemiology of microbial infections.- 7. Socioeconomic impact of antimicrobial resistance and their integrated mitigation by One Health approach.- 8. Regulations in antimicrobial drug development: Challenges, and new incentives.- 9. New insights into and updates on antimicrobial agents.- 10. Polyphenols as emerging antimicrobial agents.- 11. Antimicrobial peptides and small molecules as antibiotics substitute.- 12. Molecular mechanisms of antimicrobial resistance in S. aureus biofilms.- 13. Antimicrobial resistance: Meaning and developing realization.- 14. Chemical diversity in fungi: strategies to mitigate antimicrobial resistance.- 15. Phage therapy as an alternative treatment in the fight against AMR: Real-world problems and possible futures.- 16. Omics and in-silico approaches in the surveillance and monitoring of antimicrobial resistance.- 17. Antimicrobial activity of bioactive compounds (Thymoquinone & Eugenol) and its nanoformulations therapeutic potential.- 18. Nanoparticles as a future alternative against multiple drug resistance.- 19. Nano-cargos boarded defensins to combat multi-drug resistance.- 20. Implementation of nano-vehicles to disguise and fight multi-drug resistance.- 21. Silver nanoparticles as potent multi-drug resistant in-corporants in biomedicine.- 22. Role of gold nanoparticles against bacterial multidrug resistance (MDR): An emerging therapeutic revolution.- 23. Carbon nanoparticles: A potential cost-effective approach to counter antimicrobial resistance.- 24. Antimicrobial interfaces as augmentative strategy against antimicrobial resistance.- 25. Nano-Strategies against rising antimicrobial resistance (AMR): Metallic nanoparticles as nano-weapon.
