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Full Description
Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including S1P, neuregulin, Notch, erythropoietin, Rho-ROCK, mTOR, and more.
Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways - Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
Contents
Shaping of the tumor microenvironment by Notch signaling.- Erythropoietin signaling in the microenvironment of tumors and healthy tissues.- Neuropilin - handyman and power broker in the tumor microenvironment.- Translational landscape of mTOR signaling in integrating cues between cancer and tumor microenvironment.- Toll-like receptors signaling in the tumor microenvironment.- Rho-ROCK signaling in normal physiology and as a key player in shaping the tumor microenvironment.- S1P signaling in the tumor microenvironment.- CD200-CD200R pathway in the regulation of tumor immune microenvironment and immunotherapy.- Index.