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Full Description
Carbonyl Reductase: Design, Screening, Modification and Industrial Applications promotes the practical applications of carbonyl reductase. This book introduces the most recent advances of carbonyl reductases, including the analyzed crystal structures and structural information, the catalytic mechanism, the high-throughput screening methods, the protein engineering and the expanded applications. This book is a valuable resource for researchers and professionals interested in carbonyl reductase and chiral γ-amino alcohols production.
Contents
Section 1 Discovery and Classification of Carbonyl Reductases
1. Discovery of carbonyl reductases
2. Classification of carbonyl reductases
Section 2 Molecular Basics of Carbonyl Reductase
3. Stereoselectivity Catalytic Mechanism of Carbonyl Reductase
4. Design and Molecular Modification of Carbonyl Reductase
Section 3 Coenzyme Systems
5. Coenzyme Regeneration in Carbonyl Reduction Reaction
Section 4 Application of Stereoselectivity Carbonyl Reductase in the Synthesis of Chiral Alcohol Pharmaceutical Intermediates
6. Applications in Hypolipidemic Drugs
7. Applications in Carbapenem Antibiotics
8. Applications in Depression Treatment Drugs
9. Applications in Anti-asthma Drugs
10. Applications in Antihypertensive Drugs
11. Applications in Anticoagulant Drugs
12. Applications in Antiepileptic Drugs
13. Applications in Non-Steroidal Anti-Inflammatory Drugs
14. Applications in Anticancer Drugs
15. Applications in anti-aids Drugs
16. Applications in Adrenoceptor Agonists
Sections 5 Application of carbonyl reductases in the synthesis of other fine chemicals
17. Chirality γ- Pentolactone
18. (2S, 3S) -2,3-butanediol
19. Phenylethanol
