Description
Microbial Stress Survival explores the diversity of microbes, the microbe-host relationship, and the various strategies employed by microbes that enable them to adapt to stressful environments and persist in hostile conditions. The book aims to cover critical pathogen biology, microbial adaptation and survival strategies, and the impact of microbial resilience on therapeutic efforts. Topics include the modulation of host pathways by pathogens for their adaptation and survival; their drug tolerance and antimicrobial resistance; role of proteins in microbial stress survival; and evolutionary adaptative mechanisms of extremophiles. Microbial Stress Survival is an insightful resource for those interested in pathogen biology and the different adaptive features and resilience of microbes.- Discusses the adaptive mechanisms of microbes that allow them to cross the defensive barrier of their host- Covers the proteins responsible for growth regulation of bacteria during unfavorable conditions- Examines microbial stress response and adaption to extreme environments- Explores different bioremediation strategies for the degradation of various types of pollutants
Table of Contents
1. Two-component systems of pathogens (Mycobacterium tuberculosis/ Streptococcus pneumoniae/ Salmonella enterica / Helicobacter Pylori etc.) in stress sensing and adaptations2. Role of lipoproteins in the pathogenesis of Mycobacterium tuberculosis3. PhoPR two-component system mycobacterial virulence4. SenX3–regX3 two-component regulatory System proteins in the pathogenesis of Mycobacterium tuberculosis5. Mycobacterial membrane vesicles in host-pathogen interactions and pathogenesis6. Different growth regulation strategies of microbes for survival and reactivation during stress7. Microbial secretion system and quorum sensing8. Bacteria and biofilms as natural inhabitants of our body and biofilms in chronic infections9. Molecular level drug tolerance and resistant strategies in a diverse group of pathogenic microbes and the uses of different antimicrobial agents10. Adaptation to various antimicrobial agent (resistance) stress in diverse pathogenic microbes11. Adaptation mechanisms in the initiation factors involved in the translation process of thermophilic bacteria12. Structural adaptations in the of valine--tRNA ligases of different halophiles13. Molecular evolution steered adaptations in the phosphoglycerate and pyruvate kinase of piezophilic bacteria14. Recent advances in the survival and adaptation strategies of microbes in extreme radiation15. Cold dwelling microorganisms – A theory on psychrophilic adaptation16. Structural adaptations in the CRISPR-Cas of different thermophiles
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