Description
Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers.Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.- Includes comprehensive coverage on all available biomarkers to predict organ rejection- Provides guidance on how to interpret test results of all available biomarkers- Covers possible sources of errors in measuring biomarkers to eliminate issues of interference
Table of Contents
1. Organ transplantation: past, present, and future2. Trends in kidney transplantation3. Immunobiology in kidney transplantation4. Immunosuppression in kidney transplantation5. Challenges in the therapeutic drug monitoring of immunosuppressants6. Overview of biomarkers in kidney transplantation7. Biomarkers for ischemia reperfusion injury and delayed graft function8. Biomarkers of renal transplant rejection: yesterday, today, and tomorrow9. Biomarkers predicting the response to immunosuppressant therapy10. Biomarkers of recurrent disease after kidney transplantation11. Biomarkers of tolerance in renal transplantation12. Biomarkers for detecting opportunistic infections in renal transplant recipients13. Biomarkers for detecting nephrotoxicity due to immunosuppressant drugs14. Biomarkers for drug development in kidney transplantation15. Commercially available biomarker tests in kidney transplantation16. The unmet needs, current challenges and future directions for biomarkers in renal transplantation
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- 電子書籍
- 刃牙らへん 6 少年チャンピオン・コミ…
