Harnessing Quorum Quenching for Disease Management

著者名：Roy PhD, Arpita (EDT)/Policarpo Tonelli PhD, Fernanda Maria (EDT)/Pandit PhD, Soumya (EDT)

Academic Press（2025/10/17発売）

• 言語：ENG
• ISBN：9780443341786
• eISBN：9780443341793

Description

Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.- Offers a multidisciplinary approach to understanding quorum sensing and quorum quenching- Explores mechanisms of quorum quenching and methods available to study these- Considers quorum quenching applications across the treatment of human and plant diseases- Examines the use of nanotechnology and in silico technologies for optimizing quorum quenching

Table of Contents

PART 1: Understanding quorum quenching1. Quorum sensing and quorum quenching: a brief review2. Quorum quenching enzymes and inhibitor3. Methods to study quorum quenching4. Quorum sensing inhibitors from natural sources5. Mechanisms of quorum quenchingPART 2: Quorum quenching applications7. Inhibiting quorum sensing for antimicrobial resistance8. Inhibiting quorum sensing for disease treatment9. Genetically modified organisms to produce quorum quenching enzymes10. Quorum quenching bacteria and their application in the medical field11. Quorum quenching for biocontrol of plant diseasesPART 3: Quorum quenching: new technologies, limitation and future prospects12. Nanomaterials for quorum quenching13. In silico technologies and synthetic biology role in quorum quenching14. Main limitations and future prospects of quorum quenching strategies