Description
Richly illustrated with figures and examples and supplemented with a glossary of terms, The Evolutionary Roots of Human Brain Diseases assembles recent findings in clinical neuroscience, evolutionary biology, anthropology, and cellular biology to elucidate the origins of human brain diseases and how evolution has given rise to exclusive impacts on brain health only in humans. The book is succinct, up-to-date, and written by researchers across numerous disciplines, making it a compulsory read for clinical neurologists, psychologists, and all medical researchers interested in the brain.The book's 22 chapters cover basic science concepts behind cerebral cellular specificities or human-specific network developments, detailed discussions of neurological or psychiatric diseases and their clinical expression with an evolutionary focus, the newest imaging techniques to study the brain, future medication developments, as well as cultural and societal repercussions. Evolutionary concepts ranging from genetic pleiotropic antagonism to disease remnants of ancient behaviours crucial for survival are also presented. Insightful and innovative in its approach, this book offers a fascinating interdisciplinary dialogue on the potential repercussions of ongoing human brain evolution.
Table of Contents
Foreword by Sten GrillnerIntroduction by the Editors, Nico J. Diederich, Martin Brüne, Katrin Amunts, Christopher G. GoetzPart I: Human Brain Evolution: From Anatomy to FunctionChapter 1: Human TelencephalizationKatrin Amunts and Felix StröckensChapter 2: Evolutionary Aspects of Glial ExpansionPierre Magistretti, Patrick Hof , Corrado Cali, and Nicole AckermansChapter 3: The Contribution of Mitochondrial Evolution and Dysfunction to NeurodegenerationAnne Grünewald, Sandro Pereira, and Kobi WasnerChapter 4: Intrinsic Templates for Neurodegenerations Featuring Disease-specific Axonal or Dendritic VulnerabilityToshiki UchiharaChapter 5: Differences in Brain Gene Expression Between Humans and PrimatesGeneviève Konopka and Emre CaglayanChapter 6: Adapative Archaic IntrogressionOlga Dolgova and Oscar LaoChapter 7: Goal-directed and Habitual Behaviors: Anatomical and Functional Circuits in Health and Neurological DiseaseLedia F. Hernandez and Ignacio ObesoPart II: How Human Brain Diseases Are Impacted By Human EvolutionChapter 8: Alzheimer's Disease, the Parietal Lobes, and the Evolution of the Human GenusEmiliano Bruner and Heidi I.L. JacobsChapter 9: Parkinson's Disease - Overstrain Focused of Basal Ganglia and Brainstem NucleiNico J. Diederich and Christopher G. GoetzChapter 10: Brain Diseases Associated with Unstable RepeatsPeng Jin, Katharine Shelly, and Emily G. AllenChapter 11: The Properties of Cortico-Motoneuronal Connections and Their Evolutionary Significance for Amyotrophic Lateral SclerosisRoger LemonChapter 12: REM Sleep Behavior Disorder - Nocturnal Replay of a "Fight and Flee"Nico Diederich and Isabelle ArnulfChapter 13: Mood Disorders: An Evolutionary Psycho-Neuro-Immunological ApproachMarkus J Rantala Javier I. Borráz-León Chapter 14: Schizophrenia - Embracing the SpectrumJohn S. AllenChapter 15: Williams Syndrome and Autism - Dysfunction of Frontal NetworksKaterina Semendeferi and Isabel AugustChapter 16: ADHD - An Evolutionary View Annie SwanepoelChapter 17: Addiction - Diverted Reward and Motivation PrinciplesRoger Sullivan and Edward Hagen Part 3: Consequences and perspectives on research and clinical sciencesChapter 18: Conditions of Comparative Brain ConnectomicsKathleen Rockland, Daniel Zachlod, and Katrin Amunts Chapter 19: Are Evolutionary Concepts Helfpul in Designing Preventive Strategies for Brain Diseases?Gilberto Levy and Bruce Levin Chapter 20: Evolutionary Aspects of Neuro-PsychopharmocologyMartin Brüne, Riadh Abed, and Paul St. John-Smith Chapter 21: Ongoing Human Evolution?Frank Rühli, Maciej Henneberg, and Nicole Bender Chapter 22: Human Cultural Evolution Outpaces Biological Evolution: A Brain Connectomic ApproachJean-Pierre ChangeuxChapter 23: Concluding Remarks and Future DirectionsMartin Brüne, Katrin Amunts, Nico J. Diederich, and Christopher G. Goetz
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