Magnetic Nanoparticles in Nanomedicine

著者名：Wu, Kai (EDT)/Wang, Jian-Ping (EDT)

Woodhead Publishing（2024/06/04発売）

• 言語：ENG
• ISBN：9780443216688
• eISBN：9780443216695

Description

Magnetic Nanoparticles in Nanomedicine provides readers with the fundamental theories and principles of magnetic materials, the synthesis and surface functionalization strategies of MNPs, and the standard techniques for characterizing physicochemical properties of MNPs. Other sections review MNP-based therapies such as magnetic hyperthermia therapy, drug/gene delivery, and magnetic neurostimulation and cover MNP-based in vitro and in vivo disease diagnosis, respectively, including techniques such as magnetoresistive (MR), nuclear magnetic resonance (NMR), magnetic particle spectroscopy (MPS) biosensing platforms, magnetic resonance imaging (MRI), and magnetic particle imaging (MPI).Final chapters address biocompatibility and safety issues in applying MNPs to in vivo biomedical applications, including coverage of the toxicity of MNPs to human tissues, the immune responses of the human body to these particles, as well as blood circulation time of MNPs.- Provides a valuable tool for academics and clinicians, pushing the frontiers of magnetic-based early-stage disease diagnosis and screening- Clearly explains the synthesis, functionalization, and biocompatibility of magnetic nanoparticles- Describes micromagnetic simulation, a valuable tool for predicting the properties of magnetic nanomaterials

Table of Contents

Section I. Magnetic Nanoparticles (MNPs): Synthesis, Functionalization and Characterization1. Basics of Magnetic Materials and Magnetism2. Micromagnetic Simulation3. Current Methods for Synthesis and Surface Modifications of MNPs4. Current Characterization Techniques for MNPs Section II. MNPs for Therapy5. MNPs for Hyperthermia Therapy6. MNPs for Drug/Gene Delivery7. MNPs for NeurostimulationSection III. MNPs for In Vitro Disease Diagnosis8. Magnetoresistive (MR) Biosensor9. Nuclear magnetic resonance (NMR) Biosensor10. Magnetic Particle Spectroscopy (MPS) Biosensor11. Magnetic Separation Assisted DiagnosisSection IV. MNPs for In Vivo Disease Diagnostic Imaging12. Magnetic Resonance Imaging (MRI)13. Magnetic Particle Imaging (MPI)Section V. Biocompatibility and Immunotoxicity of MNPs14. Immunotoxicity and Safety Considerations​​​​​15. Cellular Uptake and Blood Circulation Time of MNPs