Economic Evaluation in Genomic and Precision Medicine

著者名：Mitropoulou, Christina (EDT)/Wordsworth, Sarah (EDT)/Buchanan, James (EDT)/Patrinos, George P. (EDT)

Academic Press（2023/04/19発売）

• 言語：ENG
• ISBN：9780128133828
• eISBN：9780128133941

Description

Economic Evaluation in Genomic and Precision Medicine provides an in-depth examination of essential concepts, protocols and applications of economic evaluation in genomic and precision medicine. Contributions from leading international medical geneticists and health economists compile new ways to effectively assess the costs and outcomes of different genomic care pathways, implement cost-effective medical interventions, and enhance the value of genomic and precision healthcare. Foundational chapters and discipline-specific case studies cover topics ranging from the economic analysis of genomic trial design, to health technology assessment of next-generation sequencing, ethical aspects, economic policy in genomic medicine, and pricing and reimbursement in clinical genomics.- Introduces clinicians, researchers and students to essential concepts, protocols and applications of economic evaluation in genomic and precision medicine- Demonstrates, through foundational chapters and discipline-specific case studies, how to assess the relative costs and outcomes of different genomic care pathways and implement cost-effective budgets- Establishes clear precedents on how genomic technologies can be leveraged to simultaneously reduce costs and enhance the value of healthcare- Features contributions from leading international medical geneticists and health economists that are actively evolved in economic assessments of genomic and precision medicine

Table of Contents

1. Introduction to economic evaluation in health sciences2. Foundations of pharmacogenomics and personalized medicine 3. Economic evaluation of genome-guided treatment in oncology4. Economic evaluation of rare diseases and the diagnostic odyssey5. Economic analysis of pharmacogenetic testing for HLA-based adverse drug reactions6. Economic evaluation of personalized medicine interventions in medium- and low-income countries with poor proliferation of genomics and genetic testing7. Theoretical models for economic evaluation in genomic and personalized medicine8. Using big data in economic evaluations in genomics: Challenges and opportunities9. Assessing the stakeholder environment and views towards implementation of personalized medicine in a healthcare setting10. Feasibility for pricing, budget allocation, and reimbursement of personalized medicine interventions