Description
Antioxidants Effects in Health: The Bright and the Dark Side examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants' historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.- Introduces recent information on antioxidants in a systematic way- Provides an overview of the history and function of antioxidants- Contains discussion of antioxidants including their chemistry, sources and main effects
Table of Contents
Part 1. Introduction1. Evolution of antioxidants over times2. The oxidative stress: Causes, free radicals, targets, mechanisms, affected organs, effects, indicators3. Food autooxidationPart 2. Endogenous antioxidants4. Alpha lipoic acid5. Bilirubin6. Catalase7. Coenzyme Q8. Ferritin9. Glucose-6-phosphate-dehydrogenase10. Glutathione peroxidise11. Glutathione reductase12. Gluthathione13. Superoxide dismutase14. Uric acidPart 3. Synthetic antioxidants: bright and the dark side15. Ascorbyl palmitate16. Butylated hydroxyanisole (BHA)17. Butylated hydroxytoluene (BHT)18. Erythorbic acid (D-ascorbic acid)19. Nordihydroguaiaretic acid (NDGA)20. Octyl gallate (OG)21. Propyl gallate (PG)22. tert-butylhydroxyquinone (TBHQ)Part 4. Natural occurring antioxidants: bright and the dark side23. Amino acids24. Carnosine25. Carnosol26. Carotenoids (xanthophylls and carotenes)27. Citric acid28. Coenzyme Q29. Curcumin30. Flavonoids31. Lecithin32. Lignans33. Organosulfur compounds( allyl sulphide, indoles)34. Phenolic acids35. Phytic acid36. Protein hydrolysates37. Saponins38. Selenium39. Sterols40. Stilbenes41. Tartaric acid42. Turmeric43. Uric acid44. Vanillin45. Vitamin A (retinol)46. Vitamin C47. Vitamin E (tocopherols and tocotrienols)48. Vitamin K49. ZincPart 5. Antioxidants and diseases: Beneficial and detrimental effects50. Antioxidants and cancer51. Antioxidants and cardiovascular diseases52. Antioxidants and cataracts/ age-related macular degeneration53. Antioxidants and cognitive decline in elderly54. Antioxidants and dentistry55. Antioxidants and diabetes56. Antioxidants and gastric lesions57. Antioxidants and immune functions58. Antioxidants and infertility59. Antioxidants and liver diseases60. Antioxidants and neurological disorders and psychiatric disorders61. Antioxidants and respiratory diseases62. Antioxidants and viral diseasesPart 6: Actual and future perspectives on antioxidants63. Duality: antioxidants/prooxidants64. Food and food supplements antioxidants: Targets in human antioxidant system and effects on the production of endogenous antioxidants65. Concluding remarks and future perspectives
