Description
The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field.- The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data- Concepts illustrated with over 600 color figures and molecular-imaging examples- Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development- This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications- Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented- This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications
Table of Contents
Volume 1Overview1. General Principles of Molecular ImagingBrian D. Ross and Sanjiv Sam GambhirPart I: Molecular Imaging Technologies2. Positron Emission TomographyeMagnetic Resonance Imaging Farshad Moradi, Ryan L. Brunsing, Vipul R. Sheth and Andrei Iagaru3. SPECT and SPECT/CTBrian F. Hutton, Marlies C. Goorden and Freek J. Beekman4. Principles of Micro X-ray Computed Tomography Cristian T. Badea5. Small-Animal SPECT, SPECT/CT, and SPECT/MRILing-Jian Meng and Neal H. Clinthorne6. Instrumentation and Methods to Combine Small-Animal PET With Other Imaging Modalities Andrew N. Groll and Craig S. Levin7. Functional Imaging Using Bioluminescent Reporter Genes in Living Subjects Scott K. Lyons, Kevin P. Francis and Christopher H. Contag8. Principles and Practice of Intraoperative Fluorescence Imaging Dimitris Gorpas, Vasilis Ntziachristos and Jie Tian9. Molecular Endoscopic Imaging in CancerTimo Rath, Markus F. Neurath and Raja Atreya10. Intravital Microscopy Shariq M. Usmani and Thorsten R. Mempel11. Ultrasound F. Stuart Foster and Emmanuel Cherin12. Hybrid PET-CT-Ultrasound Imaging Bertrand Tavitian and Mailyn Perez-Liva13. Photoacoustic Molecular Imaging: Principles and Practice Junjie Yao and Lihong V. Wang14. Inhaled Gas Magnetic Resonance Imaging: Advances, Applications, Limitations, and New Frontiers Alexander M. Matheson, Caleb Thompson and Grace Parraga15. Magnetic Particle Imaging for Vascular, Cellular and Molecular Imaging Prashant Chandrasekharan, Zhi Wei Tay, Xinyi Y. Zhou, Elaine Y. Yu, Barry K.L. Fung, Caylin Colson, Benjamin D. Fellows, Yao Lu, Quincy Huynh, Chinmoy Saayujya, Paul Keselman, Daniel Hensley, Kuan Lu, Ryan Orendorff, Justin Konkle, Emine Ulku Saritas, Bo Zheng, Patrick Goodwill and Steven Conolly16. Optogenetics Maria G. Paez Segala and Loren L. Looger17. Imaging Mass Spectrometry Richard R. Drake, Danielle A. Scott and Peggi M. Angel18. CEST (Chemical Exchange Saturation Transfer) MR Molecular Imaging Guanshu Liu and Peter C.M. van Zijl19. Molecular Imaging Using Raman Scattering Stefan Harmsen and Sanjiv Sam Gambhir20. Synchrotron-Based Dynamic Lung Imaging Stephen Dubsky21. Light-Sheet Fluorescence Microscopy for Multiscale Biological Imaging Jae-Byum Chang, Ruixuan Gao and Fei Chen22. Cerenkov Imaging Edwin C. Pratt, Ryo Tamura and Jan Grimm23. Near-Infrared II Optical Imaging Shuqing He and Zhen ChengPart II: Chemistry of Molecular Imaging24. Chemistry of Molecular Imaging: An Overview Silvio Aime, Fabio Travagin, Enzo Terreno and Giovanni B. Giovenzana25. PET RadiochemistryHenry F. VanBrocklin26. SPECT RadiochemistryTheodosia Maina and Mathew Thakur27. The Chemistry in Surface Functionalization of Nanoparticles for Molecular Imaging 493Xianchuang Zheng, Joanna Wang and Jianghong Rao28. Newer Bioconjugation Methods Ahmet Krasniqi, Catarina Xavier and Nick Devoogdt29. Targeted Antibodies and Peptides Michael R. Lewis, Cathy S. Cutler and Silvia S. Jurisson30. Antibody-Based Molecular Imaging Kathryn M. Tully, Veronica L. Nagle, Joshua A. Korsen and Jason S. Lewis31. Hyperpolarized Magnetic Resonance With Dissolution Dynamic Nuclear Polarization: Principles and ApplicationsJan H. Ardenkjaer-Larsen32. Magnetic Resonance Imaging AgentsCuihua Wang, Elisenda Rodriguez and John W. Chen33. Optical Imaging AgentsLuisa Ottobrini, Cristina Martelli and Giovanni Lucignani34. Photoacoustic Molecular Imaging With Exogenous AgentsLiming Nie, Yajing Liu and Xiaogyuan Chen35. Ultrasound Contrast AgentsMark A. Borden, Paul A. Dayton, Connor Slagle and Rachel W. Walmer36. Theranostics: Agents for Diagnosis and TherapyFay Nicolson and Moritz F. Kircher37. Magnetic NanoparticlesAhmad Amirshaghaghi, Zhiliang Cheng, Lee Josephson and Andrew Tsourkas38. Aptamers for Molecular Imaging Fre´de´ric Duconge´39.
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