Description
With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access.The text has been thoroughly updated, with new information on biopharmaceuticals and vaccines as well as clinical development and target identification. Drug discovery and development continues to evolve rapidly and this new edition reflects important changes in the landscape.Edited by industry experts Raymond Hill and Duncan Richards, this market-leading text is suitable for undergraduates and graduates undertaking degrees in pharmacy, pharmacology, toxicology, and clinical development through to those embarking on a career in the pharmaceutical industry.- Key stages of drug discovery and development- Chapters outline the contribution of individual disciplines to the overall process- Supplemented by specific chapters on different modalities- Includes coverage of Oligonucleotide therapies; cell and gene therapy- Now comes with online access on StudentConsult
Table of Contents
Section 1 Introduction and Background1. Development of the pharmaceutical industry2. Nature of disease and purpose of therapy3. Therapeutic modalitiesSection 2 Drug Discovery4. Drug target identification5. Selecting the modality and planning the project6. High throughput screening7. Medicinal Chemistry8. Biopharmaceuticals and related molecules9. Emerging modalities: nucleotide based therapy, cell based therapy, gene therapy / Novel and Advanced Process10. Metabolism and Pharmacokinetical strategies.11. Role of pharmacology to include pharmacology of newer modalities12. In vitro in vivo translation13. VaccinesSection 3 Drug Development14. Drug development introduction15. Drug safety16. Pharmaceutical development17. Clinical development18. Clinical imaging19. Intellectual property20. Regulatory affairs21. Marketing and Patient access to medicinesSection 4 Facts and Figures22. Facts and Figures; and the Future
