Description
Tantalizing Therapeutics in Bronchopulmonary Dysplasia is a concise reference that provides an overview of emerging concepts in the understanding of lung development and injury from a molecular and cellular point-of-view, including exciting pathways that are paving the way for new options to prevent or treat Bronchopulmonary Dysplasia (BPD). The book's chapters are written by experts who are at the forefront of BPD research. Coverage includes chapters on exosomes, stem cells and miRs, as well as a section on new discoveries in BPD research with translational potential. This is a must-have reference for researchers, physicians and trainees working on BPD, lung developmental biology, and more.- Includes discussions on which aspects of the bench research in Bronchopulmonary Dysplasia are the most promising areas- Offers insights into the latest research being conducted that could potentially move to the bassinet (in the NICU)- Contains evidence-based summaries and informed opinions about existing therapies
Table of Contents
Section 1: Current Therapeutics: State of the Art1. Systemic and topical glucocorticoids to prevent BPDKristi Watterberg and Olivier Baud2. Use of caffeine for prevention of BPDAbhay Lodha, Stefani Doucette, and Vineet Bhandari3. Next Generation ventilator strategies to prevent/manage BPDMartin Keszler and Ashish GuptaSection 2: Ongoing Therapeutic Studies with Translational Potential4. End points for therapeutic trials for BPD: lessons learned from clinical trialsJudy L. Aschner and Cynthia T. McEvoy5. What can exogenous surfactant provide in the fight against BPD?Peter A. Dargaville6. Stem cells in the treatment of BPDSo Yoon Ahn, Yun Sil Chang, Won Soon ParkSection 3: Future Therapeutic Directions7. Extracellular vesicles in the therapy of BPDFlore Lesage and Bernard Thebaud8. Growth factors in the therapy of BPDHeber C. Nielsen, Anne Chetty, and Vineet Bhandari9. Antenatal approaches in the therapy of BPDAndre Gie, Ignacio Valenzuela, Thomas Salaets, Jan Deprest, and Jaan Toelen10. miRs –mere hype or master regulators in the therapy of BPD?Charitharth Vivek Lal, Vivek Shukla, Namasivayam Ambalavanan, and Vineet Bhandari11. Immune modulators for the therapy of BPDMargaret Gilfillan and Vineet Bhandari
