Description
Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the latest developments and challenges in carbonic anhydrase research. Authors describe the mechanisms of action of specific inhibitors in relation to physiological function, and present previously unpublished research on CA activators. Written by a team of in
Table of Contents
Chapter 1 Carbonic Anhydrases: Catalytic and Inhibition Mechanisms, Distribution and Physiological Roles, Chapter 2 Acatalytic CAs: Carbonic Anhydrase-Related Proteins, Chapter 3 Multiple Binding Modes Observed in X-Ray Structures of Carbonic Anhydrase Inhibitor Complexes and Other Systems: Consequences for Structure-Based Drug Design, Chapter 4 Development of Sulfonamide Carbonic Anhydrase Inhibitors, Chapter 5 QSAR Studies of Sulfonamide Carbonic Anhydrase Inhibitors, Chapter 6 Metal Complexes of Heterocyclic Sulfonamides as Carbonic Anhydrase Inhibitors, Chapter 7 Nonsulfonamide Carbonic Anhydrase Inhibitors, Chapter 8 Clinical Applications of Carbonic Anhydrase Inhibitors in Ophthalmology, Chapter 9 Cancer-Related Carbonic Anhydrase Isozymes and Their Inhibition, Chapter 10 Role of Carbonic Anhydrase and Its Inhibitors in Biological Science Related to Gastroenterology, Neurology and Nephrology, Chapter 11 Carbonic Anhydrase Inhibitors in Dermatology, Chapter 12 Carbonic Anhydrase Activators, Index
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