Description
This book reviews advances made in recombinant DNA technology as it relates to the techniques employed, and the production and testing of potentially important products such as human interferon, insulin, and growth hormone.
Table of Contents
Chapter 1 Recombinant DNA Techniques: Isolation, Cloning, and Expression of Genes. Chapter 2 From Somatostatin to Human Insulin Chapter 3 Yeast: An Alternative Organism for Foreign Protein Production Chapter 4 Background to Human Interferon. Chapter 5 Preclinical Assessment of Biological Properties of Recombinant DNA Derived Human Interferons Chapter 6 Human Clinical Trials of Bacteria-Derived Human a Interferon. Chapter 7 Large-Scale Production of Human Alpha Interferon from Bacteria Chapter 8 Direct Expression of Human Growth Hormone in Escherichia coli with the Lipoprotein Promoter. Chapter 9 Biological Actions in Humans of Recombinant DNA Synthesized Human Growth Hormone Chapter 10 The NIH Guidelines for Research Involving Recombinant DNA Molecules Chapter 10A Appendix: Viral Vectors and the NIH Guidelines Chapter 11 FDA's Role in Approval and Regulation of Recombinant DNA Drugs
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