Description
Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses.- Contains comprehensive coverage of neurogenetics- Details the latest science and its impact on our understanding of neurological, psychiatric disorders- Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Table of Contents
Section V. Dementias26. The genetic landscape of Alzheimer disease27. Frontotemporal dementia28. The genetics of dementia with Lewy bodies29. Prion diseaseSection VI. Paroxysmal Disorders30. Genetics of epilepsy31. Genetics of migraine32. Periodic paralysis33. Episodic ataxias34. Disorders of sleep and circadian rhythmsSection VII. Neuromuscular Disorders35. Facioscapulohumeral muscular dystrophy36. The genetics of congenital myopathies37. Genetic basis and phenotypic features of congenital myasthenic syndromes38. Spinal muscular atrophy39. Emerging understanding of the genotype: Phenotype relationship in amyotrophic lateral sclerosis40. Spinal and bulbar muscular atrophy41. Hereditary spastic paraplegia42. NeuropathySection VIII. Diseases of White Matter and Demyelination 43. The spectrum of adult-onset heritable white matter disorders 44. Alexander disease45. Neurogenetics of Pelizaeus-Merzbacher disease46. Multiple sclerosisSection IX. Cerebrovascular Diseases47. CADASILSection X. Major Adult Psychiatric Disorders48. Neuroepigenetics and addiction49. Genetic susceptibility in obsessive-compulsive disorderSection XI. Cancer and Phakomatoses50. Brain cancer genomics and epigenomics51. Neurofibromatosis type 152. Tuberous sclerosis complex53. Von Hippel-Lindau disease and Sturge-Weber syndrome
