Description
Recent advances in molecular and cellular biology have markedly changed our understanding of the heart, and this is having tremendous ramifications for the clinician. This unique reference offers a comprehensive and critical evaluation of this contribution in the field of cardiovascular molecular medicine providing the reader with a sense of new directions in which molecular medicine might be applied. It begins with a detailed primer that makes readily accessible recent molecular, genetic and cellular techniques. Rounding out the coverage of this exciting field are critical and comprenhesive discussions on the use of molecular, genetic and cellular techniques used to identify the etiology and pathophysiology of specific cardiac diseases.* Discusses diagnostic and therapeutic options available not only in the adult and aging individuals but also in infants/children* Numerous illustrations and flow-charts* Explans cutting-edge molecular techniques, including analysis of mitochondria, their role in cardiac dysfunction and updated analysis of Cardioprotection and Metabolic Syndrome* Presentation of recent translational studies for the treatment of cardiovascular diseases is included (e.g., gene therapy, pharmacological treatments and stem cell transplantation)
Table of Contents
BIOCHEMICAL, CELLULAR AND MOLECULAR FUNCTIONING OF THE HEARTIntroduction to Post-Genomic CardiologyMolecular and Biochemical Methodology in the Post-Genomic EraCardiovascular Gene ExpressionCellular TechniquesCardiovascular Signaling PathwaysPEDIATRIC CARDIOLOGY IN THE POST-GENOMIC ERACardiac Development: Molecular and Genetic AnalysisCongenital and Adquired Heart DiseasePOST-GENOMIC ANALYSIS OF CORONARY ARTERY DISEASE, ANGIOGENESIS AND HYPERTENSIONMolecular Basis of Lipoproteins Disorders, Atherogenesis and ThrombosisIschemia and Myocardial Infarction: A Post-Genomic AppraisalCellular Pathways and Molecular Events in CardioprotectionCardiac Neovascularization: Angiogenesis, Arteriogenesis and VasculogenesisSystemic and Pulmonary Hypertension POSTGENOMIC ANALYSIS OF THE MYOCARDIUMCardiomyopathies Heart Response to Inflammation and InfectionTHE FAILING HEARTMolecular analysis of heart failure and remodelingMOLECULAR AND GENETIC ANALYSIS OF METABOLIC DISORDERSFatty Acid and Glucose Metabolism in Cardiac DiseaseMOLECULAR GENETIC OF DYSRHYTHMIASDysrhythmias and Sudden Death GENES, GENDER AND ENVIRONMENTGender and Cardiovascular DiseaseAGING AND THE CARDIOVASCULAR SYSTEMThe Aging Heart: A Post-Genomic AppraisalLOOKING TO THE FUTUREFuture of Post-Genomic CardiologyGLOSSARYINDEX
