Description
Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.
Table of Contents
ContributorsPrefaceChapter 1 Perspectives on Receptor Autoradiography and Human Brain Text ReferencesChapter 2 Benzodiazepine, GABA and Glutamate Receptors in Cerebral Cortex, Hippocampus, Basal Ganglia, and Cerebellum Introduction Methods Results Discussion Abbreviations ReferencesChapter 3 Acetylcholine, Serotonin and ß Adrenoceptors Introduction Methodology Cholinergic Muscarinic Receptors Serotonin Receptors ß-Adrenergic Receptors Discussion Abbreviations ReferencesChapter 4 Multiple Serotonin Receptors in the Human Brain Labeling of 5-HT Receptors in the Brain for Autoradiography Distribution of 5-HT Receptors in Human Brain Conclusion and Future Trends Abbreviations ReferencesChapter 5 Distribution of Multiple Opioid Receptors in the Human Brain Introduction Technical Comments Mu Opioid Receptors Delta Opioid Receptors Kappa Opioid Receptors Conclusion Abbreviations ReferencesChapter 6 Angiotensin II Receptors in the Human Central Nervous System Brain Renin-Angiotensin System Experimental Methods Distribution of Ang II Receptor Binding in the Human Brain Discussion Conclusion Abbreviations ReferencesChapter 7 Angiotensin-Converting Enzyme in the Human Brain Angiotensin-Converting Enzyme in the Central Nervous System Methods Results Discussion Conclusion Abbreviations ReferencesChapter 8 Codistribution of Receptors in the Human Cerebral Cortex Introduction Material and Method Receptor Codistribution in the Human Hippocampus Receptor Codistribution in the Human Primary Visual Cortex Receptor Codistribution in the Human Frontal Agranular Cortex Receptor Codistribution in the Human Medial Temporal Gyrus General Aspects of Receptor Codistributions in the Human Cortex Abbreviations ReferencesChapter 9 Receptors in the Human Spinal Cord Benzodiazepine/GABAA Receptors Opiate Receptors Neurotensin Receptors Cholinergic Receptors Adenosine Receptors Excitatory Amino Acid Receptors ReferencesIndex
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