The Funding of Biopharmaceutical Research and Development

著者名：Williams, David R

Woodhead Publishing（2013/10/31発売）

• 言語：ENG
• ISBN：9781907568947
• eISBN：9781908818386

Description

The funding of biopharmaceutical research and development provides a comprehensive critical review of the funding of research and development (R&D) in the human biopharmaceutical market sector. It addresses both private and public funding sources available in the US and internationally. The biopharmaceutical market is among the most research-intensive market sectors globally. Clinical researchers face a multitude of public and private funding options with respect to bringing their idea or innovation to market. These funding options are continually changing and complex, and are expected to decrease in the near future. A lack of understanding of the scale, scope, and inner workings of the funding aspects of R&D can, at times, act as a barrier for all involved, and can slow down or even eliminate the R&D process. The book lessens these barriers by describing the theoretical underpinnings, present practice, and trends in R&D funding in this market sector, both in the US and internationally. This includes a review and discussion of public-private partnership activity and their inner-workings, noting the complementary relationship between public and private funding. The book also contains an overview of the inner-workings of strategic alliance activity, including the advantages and disadvantages for each party. It goes on to provide an outline of venture capital activity, detailing the methods by which venture capital firms raise capital and are organized, a description of the venture capital-entrepreneur arrangement, and the effects of this arrangement. The book also presents an overview of the IPO process and the various fates of firms going public.- Presents a comprehensive view of the funding issues of R&D in this market sector, adopting a theory-to-practice approach- A comprehensive and analytical review of the biopharmaceutical R&D literature and practice- An overview of the various and competing/complementary theories of the firm and valuation methods as they apply to biopharmaceutical R&D

Table of Contents

DedicationList of figures and tablesGlossaryPrefaceAbout the authorChapter 1: Introduction to the biopharmaceutical marketAbstract:1.1 Introduction1.2 Synopsis of the development of the biopharmaceutical market sector1.3 Global growth of research and biopharmaceuticals1.4 Biopharmaceutical and healthcare value chain1.5 Demand for biopharmaceuticals1.6 Approval process1.7 Generic medicines1.8 Pricing of drugs1.9 Summary1.10 ReferencesChapter 2: Synopsis of theories of the firm and valuation methodsAbstract:2.1 Introduction2.2 The neoclassical perfect competition model2.3 Industrial organization economics2.4 Resource-based view of the firm2.5 Innovation and entrepreneurship2.6 Valuation2.7 Real options2.8 Final words on valuations2.9 Corporate control2.10 Summary2.11 ReferencesChapter 3: Innovation and the merging of the pharmaceutical and biotechnology industriesAbstract:3.1 Patents and patent protection3.2 Standards and S-curves3.3 Real options reasoning3.4 Pro-innovation bias3.5 Summary3.6 ReferencesChapter 4: The funding of basic research and publicâ€"private partnershipsAbstract:4.1 Introduction to research funding in the U.S.4.2 Research funding in the European Union4.3 Research funding in Asia4.4 Technology transfer4.5 Technology transfer offices4.6 Bioclusters4.7 Biocenters4.8 Spill-overs and the diffusion of biopharmaceuticals4.9 Summary4.10 ReferencesChapter 5: Strategic alliancesAbstract:5.1 Introduction to strategic alliances5.2 Forms of strategic alliances5.3 Models of the management of multiple alliances5.4 Not all alliances are strategic5.5 Opportunism in strategic alliances5.6 Summary5.6 ReferencesChapter 6: Angel and venture capitalAbstract:6.1 Introduction to angel investors and venture capital6.2 Venture capital staging6.3 Venture capital history6.4 Ownership structure6.5 Venture capital and the entrepreneur6.6 Venture capital around the world6.7 Summary6.8 ReferencesChapter 7: The initial public offeringAbstract:7.1 An introduction to the initial public offering7.2 A brief synopsis of the history of stock exchanges7.3 The IPO process in the United States7.4 IPOs around the U.S.7.5 Research and development expenditures and financial condition7.6 IPO performance7.7 Venture capital involvement7.8 IPO as exit7.9 IPO activity around the world7.10 Summary7.11 ReferencesChapter 8: ConclusionAbstract:8.1: ReferencesIndex