Full Description
This volume deals mainly with the specialized aspect of toxins and drug discovery. Man has been using natural resources especially plants to treat diseases from very early times in history of mankind. Although many drugs derived from plants and microbes have been discovered and being used in clinical practice, not many drugs have been developed from venoms and toxins although many laboratories worldwide are actively working on it. This volume describe some of the recent developments in this research area, such as snake venoms, conotoxins , bioinformatics in drug discovery from peptide toxins.
Contents
Crotoxin from Crotalus durissus terrificus and Crotoxin-Related Proteins: Structure and Function Relationship.- Dexamethasone Antagonizes Myotoxic and Inflammatory Effects Induced by Bothrops Snake Venoms.- Inflammatory Action of Secretory PLA2 from Snake Venoms.- Natural Inhibitors of Snake Venom Metallopeptidases.- Production and Utilization of Snake Antivenoms in South America.- Snake Venom Components as Basis for Biologically Active Synthetic Peptides.- Antiproliferative Effects of Snake Venom Phospholipases A2 and Their Perspectives for Cancer Treatment.- Conotoxins and Drug Discovery with Special Reference to Hainan Species.- Conotoxins as Tools in Research on Nicotinic Receptors.- Random Peptide Library for Ligand and Drug Discovery.- Synthetic Peptides and Drug Discovery.- Bee Venom and Pain.- L-Amino Acid Oxidase from Venoms.- Myotoxin Inhibitors.- Computational Approaches for Animal Toxins to Aid DrugDiscovery.- Toad Poison and Drug Discovery.- Venoms as Sources of Novel Anti-parasitic Agents.- Intriguing Cystine-Knot Miniproteins in Drug Design and Therapeutics.- Intriguing Cystine-Knot Miniproteins in Drug Design and Therapeutics.
