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Full Description
Epigenomics deals in detail with the concepts, principles, procedures, developments, limitations, advantages, applications and future prospects of different areas of epigenomics in a comprehensive manner. It provides concise yet complete knowledge on the many aspects of the basic and most recent methods and applications in epigenomics, a branch of epigenetics that deals with the mechanisms such as DNA modifications, histone modifications, RNA modifications, small and long non-coding RNAs, chromatin remodeling, which are involved in epigenetic control of gene expression without involving variations in DNA sequences. These regulatory mechanisms lead to phenotypic variations. These epigenetic mechanisms can be exploited for crop improvement and cure of human diseases. Epigenomics strives to understand the role of epigenetic marks (chemical tags) in the development of phenotype. This understanding provides epigeneticists to apply epigenomics in medicine and agriculture.
Self-explanatory adequately labelled figures have been the special emphasis throughout.
This book is primarily designed for senior undergraduate and graduate level (M.Sc. and Ph.D.) students studying epigenetics in conventional, agricultural and medicinal universities. This book will be a useful reference text for teachers and researcher in any discipline of life sciences, agricultural sciences, medicine, and biotechnology.
Contents
1. Introduction
2. DNA Methylation Analysis
3. Histone Modification Analysis
4. RNA Modification Analysis
5. Epigenetic Analysis
6. Epigenetic Profiling and Epigenetic Landscape
7. Epigenomics
8. Epigenomes
9. Epigenome Editing
10. RNA Editing and its Programmability
11. Epitranscriptomics
12. Applications of Epigenomics
Glossary
Index
