尿石症 Nephron. Vol.98/2 Urolithiasis : A Special Issue （2004. 102 p. w. figs.）

Mitarbeit: Berlyne, Geoffrey M./ Giovannetti, S./ Ed. by W. G. Robertson. With contribution of P. Jaeger and R. J. Unwin

KARGER（2004発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 102 p.
• 商品コード 9783805578523

基本説明

Special Issue: 'Nephron 2004, Vol. 98, No. 2'.

Full Description

Nephrolithiasis is a multifactorial problem that requires input from several disciplines within the biomedical field. This publication focuses on the main topics of current interest including the basic mechanisms of crystal formation within the renal tubules and the relative roles of supersaturation and of inhibitors and promoters of crystallisation in the stone-forming process. It also includes studies on the molecular basis of the genetic disorders that predispose to stone-formation and the nutritional and pathophysiological processes that lead to an increase in the risk of stone-formation in the population. This is followed by a series of papers comparing the two main theories of stone-formation - the 'Free-Particle Model' and the 'Fixed-Particle Model' - by means of studies on the crystallisation of calcium salts within the renal tubules, on the renal tubular epithelial cell surface and within renal tubular cells. Finally, there are three papers on the clinical management of patients with stone disease including a separate article on paediatric stones, a problem that seems to have been increasing in many western countries over the past three decades. The publication should be read by all who have an active interest in the causes and management of kidney stone formation, including nephrologists, urologists, clinical biochemists, endocrinologists, nutritionists, molecular geneticists and epidemiologists. It also contains matter of interest to clinical nurse practitioners and general practitioners.

Contents

nephron Clinical Practice Aetiological Factors in Paediatric Urolithiasis: van't Hoff, W.G. Medical Management of Urinary Stone Disease: Pak, C.Y.C. Renal Stone Disease: The Urological Perspective: Amiel, J.; Choong, S. nephron Experimental Nephrology Molecular Aetiology of Primary Hyperoxaluria Type 1: Danpure, C.J. The Molecular Basis of Cystinuria: Goodyer, P. Hypophosphatemia and Calcium Nephro-lithiasis: Prie, D.; Beck, L.; Silve, C.; Friedlander, G. Role of Renal Epithelial Cells in the Initiation of Calcium Oxalate Stones: Khan, S.R. Intracellular Events in the Initiation of Calcium Oxalate Stones: J onassen, J.A.; Cao, L.-C.; Honeyman, T.; Scheid, C.R. nephron Physiology An Overview of Divalent Cation and Citrate Handling by the Kidney: Unwin, R.J.; Capasso, G.; Shirley, D.G. Kidney Models of Calcium Oxalate Stone Formation: Robertson, W.G. Clinical Value of Crystalluria and Quantitative Morphoconstitutiona l Analysis of Urinary Calculi: Daudon, M.; Jungers, P. Macromolecules and Urolithiasis: Parallels and Paradoxes: Ryall, R. L. Osteopontin and Calcium Stone Formation: Kleinmann, J.G.; Wesson, J.A.; Hughes, J. Microorganisms and Calcium Oxalate Stone Disease: Goldfarb, D.S. Role of Nutrition in the Formation of Calcium-Containing Kidney Sto nes: Taylor, E.N.; Curhan, G.C. Role of Dietary Intake and Intestinal Absorption of Oxalate in Calc ium Stone Formation: Jaeger, P.; Robertson, W.G.