Adrenergic Activators and Inhibitors (Handbook of Experimental Pharmacology 54 / 2) （2011. xxii, 938 S. XXII, 938 p. 244 mm）

Mitarbeit:Aviado, D.M./ Bowman, W.C./ Burnstock, Geoffrey/ Greven, J./ Hannappel, J./ Juul, P./ Kahan, A./ Kovacs, L./ Micozzi, M.S./ Osswald, H./ Owens, C.W.I./ Potter, D.E./ Prichard, B.N.C./ Rahn, K.H

SPRINGER, BERLIN; SPRINGER BERLIN HEIDELBERG; SPRINGE（2011発売）

SPRINGER, BERLIN; SPRINGER BERLIN HEIDELBERG; SPRINGE（2011発売）

• 製本 Paperback:紙装版/ペーパーバック版／ページ数 938 p.
• 言語 ENG
• 商品コード 9783642675867

Description

(Table of content)
of Part II.- Section IV: Effects on Organ Systems Other Than the Nervous and the Cardiovascular System.- 1 Systemic Pharmacology of Adrenergic Activators and Inhibitors: Effects on the Respiratory System.- 2 Effects of Adrenergic Activators and Inhibitors on the Skeletal Muscles.- 3 Systemic Pharmacology of Adrenergic Agonists and Antagonists: Effects on the Digestive System.- 4 Effects of Adrenergic Activators and Inhibitors on the Endocrine System.- 5 Systemic Pharmacology of Adrenergic Activators and Inhibitors: Effects on the Genital System.- 6 Effects of Adrenergic Activators and Inhibitors on Kidney Function.- 7 Effects of the Adrenergic Activators and Inhibitors on the Urinary Tract.- 8 Miscellaneous Effects: Effects of Adrenergic Activators and Inhibitors on the Eye.- 9 Effects of Adrenergic Activators and Inhibitors on the Sweat Glands.- Section V: Kinetics, Biotransformation, Toxic Effects and Clinical Implications.- 1 Kinetics and Biotransformation of Adrenergic Activators and Inhibitors: Adrenergic Alpha- and Beta-Receptor Activators.- 2 Kinetics and Biotransformation of Adrenergic Activators and Inhibitors: Adrenergic Transmitter Releasing Agents.- 3 Kinetics and Biotransformation of Adrenergic Inhibitors.- 4 Toxic Effects of Adrenergic Nerve-End Inhibitors, Neural Transmitter Depleting Agents and False Transmitters.- 5 Clinical Features of Adrenergic Agonists and Antagonists.- Author Index.ha-Receptor Blocking Agents.- I. Phenoxybenzamine and Acute Pulmonary Insufficiency.- 1. Correction of Pulmonary Vascular Consequences of Hypoxemia.- 2. Blockade of Pulmonary Vasoconstriction Induced by Catecholamines.- II. Tolazoline and Chronic Pulmonary Hypertension.- III. Phentolamine and Acute Ventricular Failure.- IV. Thymoxamine and Acute Bronchial Asthma.- H. Adrenergic Beta-Receptor Blocking Agents.- I. Nonselective Adrenergic Beta-Receptor Blocking Agents.- 1. Propranolol.- 2. Sotalol.- 3. Pindolol.- 4. Dichloroisoproterenol.- II. Cardioselective Beta-Receptor Blocking Agents.- 1. Practolol.- 2. Acebutolol.- 3. Atenolol.- 4. Bunitrolol.- I. Adrenergic Neuron Blocking Agents.- I. Bretylium.- II. Reserpine.- III. Guanethidine.- IV. Methyldopa.- J. Concluding Remarks.- 1. Nasal Congestion and Decongestion.- 2. Bronchial Mucosal Decongestion.- 3. Bronchodilation.- 4. Bronchoconstriction.- 5. Pulmonary Vasodilation.- 6. Pulmonary Vasoconstriction, Congestion, and Edema.- 7. Bronchial Circulation.- References.- 2 Effects of Adrenergic Activators and Inhibitors on the Skeletal Muscles.- A. Introduction.- B. Direct Action on Contractions of Nonfatigued Muscles.- I. Fast-Contracting Muscles.- II. Slow-Contracting Muscles.- III. Other Sympathomimetic Amines and Adrenoceptor Blocking Drugs.- IV. Adrenoceptors.- V. Electrical and Ionic Changes.- 1. Resting Membrane Potential.- 2. Action Potentials.- VI. Effect of Anaesthetic.- VII. Mechanism of Action.- C. Muscle Spindles.- D. Human Muscles.- I. Evoked Contractions.- II. Tremor.- 1. Unwanted Effect of Sympathomimetic Bronchodilators.- 2. Parkinsonian Tremor.- 3. Some Other Types of Tremor.- III. Therapy of Spasticity.- IV. Therapy of Hyperkalaemic Familial Periodic Paralysis.- E. Effects on Chronically Denervated Muscles.- I. Fibrillation.- II. Membrane Potential.- F. Actions on Neuromuscular Transmission.- I. Endplate Potential and Miniature Endplate Potentials.- II. Mechanisms of Action.- G. Effects on Fatigued Muscles.- H. Summary of Effects of Adrenaline.- I. Effects Unrelated to Adrenergic Mechanisms.- I. Adrenergic Neurone Blocking Drugs.- II. Beta-Adrenoceptor Blocking Drugs.- 1. Plasma Membrane.- 2. Sarcoplasmic Reticulum.- References.- 3 Systemic Pharmacology of Adrenergic Agonists and Antagonists: Effects on the Digestive System.- A. Introduction.- B. Alpha- and Beta-Adrenoceptor Agonists.- I. Effect on Motility.- 1. Introduction.- 2. Effect on Non-Sphincteric Smooth Muscle.- 3. Effect on Sphincteric Smooth Muscle.- 4. Effect on Acetylcholine Release from Enteric Neurones.- 5. Effect on Noradrenaline Release from Adrenergic Neurones.- 6. Mechanism of Action.- II. Effect on Gastro-Intestinal Vasculature.- III. Effect on Gastric and Intestinal Secretion.- 1. Action of Alpha-and Beta-Adrenoceptor Agonists.- 2. Mechanism of Action.- IV. Effect on Absorption.- V. Summary.- C. Adrenergic Transmitter Releasing Agents.- I. Introduction.- II. Effect on Motility.- III. Effect on Gast

Contents

of Part II.- Section IV: Effects on Organ Systems Other Than the Nervous and the Cardiovascular System.- 1 Systemic Pharmacology of Adrenergic Activators and Inhibitors: Effects on the Respiratory System.- 2 Effects of Adrenergic Activators and Inhibitors on the Skeletal Muscles.- 3 Systemic Pharmacology of Adrenergic Agonists and Antagonists: Effects on the Digestive System.- 4 Effects of Adrenergic Activators and Inhibitors on the Endocrine System.- 5 Systemic Pharmacology of Adrenergic Activators and Inhibitors: Effects on the Genital System.- 6 Effects of Adrenergic Activators and Inhibitors on Kidney Function.- 7 Effects of the Adrenergic Activators and Inhibitors on the Urinary Tract.- 8 Miscellaneous Effects: Effects of Adrenergic Activators and Inhibitors on the Eye.- 9 Effects of Adrenergic Activators and Inhibitors on the Sweat Glands.- Section V: Kinetics, Biotransformation, Toxic Effects and Clinical Implications.- 1 Kinetics and Biotransformation of Adrenergic Activators and Inhibitors: Adrenergic Alpha- and Beta-Receptor Activators.- 2 Kinetics and Biotransformation of Adrenergic Activators and Inhibitors: Adrenergic Transmitter Releasing Agents.- 3 Kinetics and Biotransformation of Adrenergic Inhibitors.- 4 Toxic Effects of Adrenergic Nerve-End Inhibitors, Neural Transmitter Depleting Agents and False Transmitters.- 5 Clinical Features of Adrenergic Agonists and Antagonists.- Author Index.