Full Description
This volume contains the proceedings of a symposium organized by the IPSEN Foundation and held in Lille, France in October 1989. It includes data on imaging techniques (computed tomography, photon emission computed tomography, nuclear magnetic resonance), neuropathology, neurochemistry and molecular biology. It provides an interpretation of Alzheimer's disease with respect to cerebral topography and its implications.
Contents
Topography of Alzheimer's Disease: Involvement of Association Neocortices and Connected Regions; Pathological, Metabolic and Cognitive Correlations; Relation to Evolution.- Cellular Pathology in Alzheimer's Disease: Implications for Corticocortical Disconnection and Differential Vulnerability.- Distribution of Neurochemical Deficits in Alzheimer's Disease.- Topography of Lesions in Alzheimer's Disease: A Challenge to Morphologists.- Computer Tomography and Study of the Anatomical Changes in Alzheimer's Disease.- Could "Leuko-araiosis" Be Secondary to Wallerian Degeneration in Alzheimer's Disease?.- Topographical Comparison of Lesions in Trisomy 21 and Alzheimer's Disease: A Study with PET, Anatomical and Neuropathological Investigations.- Cognitive Deficits and Local Metabolic Changes in Dementia of the Alzheimer's Type.- Patterns of Cerebral Metabolism in Degenerative Dementia.- Cortical Functional Impairment in Dementia of the Alzheimer Type: Studies with Positron Emission Tomography.- Brain Imaging with SPECT in Alzheimer's Disease.- Hemodynamic Subtypes of Dementia of the Alzheimer Type: Clinical and Neuropsychological Characteristics.- Nuclear Magnetic Resonance Study of Phospholipid Metabolites in Alzheimer's Disease.- Summary Comments on Presentations.
