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Full Description
This book describes how methodologies in biochemistry, molecular and cellular biology, electromagnetic bioeffects, and nanotechnology were brought together to construct a nanostructure that is a composite of nucleic acid, carbon nanotube, paramagnetic metallic nanoparticles, and aromatic polymer that is responsive to nonionizing electromagnetic radiation, RFR to microwaves. It demonstrates that the construct can act as a redox catalyst accelerated by nonionizing electromagnetic radiation, and also as a conveyor of genetic modification of specifically targeted eukaryotic and prokaryotic cells. The scientific knowledge necessary to accomplish this is described and step-by-step progress supported by data and examples are noted. The general purpose is to show how such interdisciplinary approaches can lead to disruptive technologies.
This book is most valuable to those (molecular biologists, vaccinologists, biomedical engineers, microbiologists) looking for more externally controllable gene vectors, antimicrobials, and antiparasitics, using a totally new nanoparticle platform. Those pursuing biological applications of nanotechnology will also be interested. This text has uniquely multidisciplinary approaches, drawing together chemistry, physics, molecular biology, biochemistry, and biomedical and electrical engineering.
Contents
Preface.- Introduction.- Foundation Principles and Dosimetry of Radiofrequency Radiation.- Theory and Measurement: Relaxation vs Resonance.- Phenomenology of RFR Absorption by Biological Molecules and Membranes.- Splitting Hairs: Fine and Hyperfine Splitting and Free Radicals.- Required Characteristics of a Nanostructure Radiofrequency and Microwave Absorbing Vector.- Seeking Explanations for Paradoxical Responses: Bringing It All Together.- Nonionizing Electromagnetic Radiation Driven Microbiological Effects.- Effects on Eukaryotic Cells of Biosynthesis of Radiofrequency and Microwave Radiation Absorbing Polymer.- Moving toward a Totally Synthetic Autonomous Nanoparticle.- Future Applications Beyond Microbial Killing: Promise or Peril?.- Index.
