糖質バイオ技術の最前線 Advances in Glycobiotechnology (Advances in Biochemical Engineering/biotechnology)

Rapp, Erdmann (EDT)/ Reichl, Udo (EDT)

Springer Nature Switzerland AG（2021/07発売）

• 製本 Hardcover:ハードカバー版／ページ数 463 p.
• 商品コード 9783030695897

Full Description

This book reviews the latest trends in glycobiotechnology, it offers an authoritative discussion about future directions of glycoengineering, and it provides a comprehensive overview about the current and emerging approaches to identify, quantify and characterize glycosylated proteins.

Divided into 14 chapters, the book outlines recombinant glycoprotein expression in mammalian cells, insect cells, yeast, and bacterial systems. It covers the chemical and enzymatic syntheses of glycans and glyconjugates, and addresses the impact of glycosylation on protein function for the development of biologicals including vaccines. In the final chapters of the book, readers will discover more about the state-of-the-art in glycomics, glycoproteomics and glycan array technologies.

Contents

Glyco-engineering of mammalian expression systems on process level.- Glyco-engineering of mammalian expression systems on cellular level.- Glyco-engineering of insect cell expression systems.- Glyco-engineering of yeast expression systems.- Glyco-engineering of plant(cell) expression systems.- Glyco-engineering of bacteria expression systems.- Chemical synthesis of glycans and glycoconjugates.- Enzymatic synthesis of glycans and glycoconjugates.- The interplay/impact of glycosylation and/on protein function for recombinant proteins and mAbs.- The interplay/impact of glycosylation and/on protein function for recombinant proteins and mAbs.- The interplay/impact of glycosylation and/on protein function for bacterial vaccines.- Glycomicstechnologies.- Glycoproteomicstechnologies.- Glycan array technologies.