Full Description
Silk represents an excellent source of natural biomaterials, and silk-based biopolymers have been used in numerous drug delivery applications. Silk has a proven track record in biomedicine owing to its superior compatibility with the human body, its superb mechanical characteristics, and its controllable propensity to decay. Due to its robust biocompatibility and its less immunogenic, non-toxic, non-carcinogenic, and biodegradable properties, silk has been widely used in biological and biomedical fields, proving to be a more efficient manner for the treatment of various diseases.
This book presents a comprehensive review of silk-based biopolymer drug delivery systems, providing an introduction and going on to detail the chemistry, collection, characterization, functionalization, and numerous silk-based applications in the pharmaceutical industry and healthcare fields. It discusses its uses for oral drug delivery, for vaccine delivery systems, as natural mucoadhesive polymers for controlled drug delivery, for wound healing, etc.
Exploring the many promising applications of silk-based proteins in the field of drugs and gene delivery and biomedical applications, the book emphasizes recent advancements made by academicians, researchers, and industry and regulatory scientists. It provides methodologies for the design, development, and selection of silk-based proteins in drug delivery for therapeutic applications.
Contents
Preface Introduction 1. Silk: Source, Chemistry, and Properties 2. Extraction and Characterization of Sericin and Silk Fibroin Protein 3. Biodegradation of Silk-Based Proteins 4. Role of Silk-Based Proteins for Biomedical and Healthcare Systems 5. Silk-Based Proteins as Natural Mucoadhesive Polymers for Controlled Drug Delivery 6. Role of Silk-Based Nanocarriers System in Drug and Gene Delivery 7. The Silk Symphony: Microparticulate Systems Orchestrating Drug Delivery Advancements 8. Role of Silk-Based Protein in Oral Drug Delivery 9. Role of Silk-Based Proteins in Transdermal Drug Delivery 10. Silk Based Proteins for Vaccine Delivery 11. Silk-Based Protein Drug Delivery Systems in Cancer Therapy 12. Functionalized Silk-Based Protein in Drug Delivery and Gene Delivery 13. Silk-Based Hydrogels in Drug Delivery 14. Silk-Based Protein for Wound Healing and Implantable Drug Delivery 15. Silk Fibroin Protein-Based Scaffolds: Vital Aspects and Applications 16. Miscellaneous Applications of Silk-Based Proteins: A Comprehensive Update 17. Patents and Clinical Trials of Silk-Based Drug Delivery Systems Index
