Mechanistic Enzymology and Drug Design : Clinically Used Enzyme Inhibitors (Rsc Drug Discovery)

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Mechanistic Enzymology and Drug Design : Clinically Used Enzyme Inhibitors (Rsc Drug Discovery)

Honek, John F./ Su, Zhengding/ Thurston, David E (EDT)/ Fox, David (ED

Royal Society of Chemistry（2013/12発売）

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製本 Hardcover:ハードカバー版／ページ数 250 p.
言語 ENG
商品コード 9781849730150
DDC分類 572

基本説明

Focuses on enzyme mechanisms, introduces key drugs that target each type and subtype of enzyme and describes, with figures and arrow-pushing diagrams, how these inhibitors work including diagrams of the active site and how the inhibitor binds to the enzyme.

Full Description

1. Discusses enzyme targets that have been used to develop drugs2. There are many new drugs being developed that particularly target specific enzymes.3. Biochemists, medicinal chemists, academia and industry4. Biomolecular science series, MedChemComm5. The book will survey enzyme targets that have successfully been used to develop clinically-utilized drugs and to describe in detail how these drugs inhibit these particular enzymes.

Mechanistic Enzymology and Drug Design; EC Enzyme Class 1Oxidoreductases; EC Enzyme Class 2: Transferases; EC Enzyme Class 3: Hydrolases; EC Enzyme Class 4: Lyases; EC Enzyme Class 5: Isomerases; EC Enzyme Class 6: Ligases; Where do we go from here?