基本説明
This comprehensive survey presents the essential clinical facts concerning malignant and nonmalignant blood diseases, detailing diagnostic methods, angiostatic drugs, the very latest therapies, classifications, scientific controversies, and clear treatment recommendations.
Full Description
Over the past few decades the powerful methods of statistical physics and Euclidean quantum field theory have moved closer together, with common tools based on the use of path integrals. The interpretation of Euclidean field theories as particular systems of statistical physics has opened up new avenues for understanding strongly coupled quantum systems or quantum field theories at zero or finite temperatures.
Accordingly, the first chapters of this book contain a self-contained introduction to path integrals in Euclidean quantum mechanics and statistical mechanics. The resulting high-dimensional integrals can be estimated with the help of Monte Carlo simulations based on Markov processes. The most commonly used algorithms are presented in detail so as to prepare the reader for the use of high-performance computers as an "experimental" tool for this burgeoning field of theoretical physics.
Several chapters are then devoted to an introduction to simple lattice field theories and a variety of spin systems with discrete and continuous spins, where the ubiquitous Ising model serves as an ideal guide for introducing the fascinating area of phase transitions. As an alternative to the lattice formulation of quantum field theories, variants of the flexible renormalization group methods are discussed in detail. Since, according to our present-day knowledge, all fundamental interactions in nature are described by gauge theories, the remaining chapters of the book deal with gauge theories without and with matter.
This text is based on course-tested notes for graduate students and, as such, its style is essentially pedagogical, requiring only some basics of mathematics, statistical physics, and quantum field theory. Yet it also contains some more sophisticated conceptswhich may be useful to active researchers in the field. Each chapter ends with a number of problems - guiding the reader to a deeper understanding of some of the material presented in the main text - and, in most cases, also features some listings of short, useful computer programs.
Contents
Basic Biology of Hemopoiesis.- Molecular Biology and Cytokines.- Supportive Care in Hematology.- Transplantation of Stem Cells From Bone Marrow, Peripheral Blood, and the Umbilical Cord.- Anemias.- Hemolytic Anemias.- Leukocytosis, Leukopenia, and Other Reactive Changes of Myelopoiesis.- The Myeloproliferative Syndromes.- Acute Myelogenous Leukemias.- Acute Lymphoblastic Leukemias.- Myelodysplastic Syndromes.- Aplastic Anemias.- Lymphocytosis, Lymphocytopenia, Lymphadenopathy, and Splenomegaly.- Hodgkin's Lymphoma.- The Non-Hodgkin's Lymphomas.- Multiple Myeloma and Related Paraproteinemias.- Congenital and Acquired Immunodeficiencies.- Infections Relevant to Hematology.- Basic Principles of Hemostasis.- Bleeding Disorders.- Thrombophilia, Thromboembolic Disease, and Antithrombotic Therapy.- Transfusion Medicine and Immunohematology.- Storage Disorders in Hematology.
