基本説明
For each tumor type the authors succinctly discuss the key aspects of their clinical presentation, cytology, diagnosis, nuclear isotope scanning evaluation, cellular and biochemical markers, imaging by MRI or CT, monitoring, surgery, pathology, post-operative care, and prognosis.
Full Description
are new to this edition. The authors provide not only the The second edition of Thyroid Cancer: A Comp- most current review of their respective areas, but also their hensive Guide to Clinical Management marks the pub- own recommendations and approach. The reader is fo- cation of a markedly updated and expanded volume that warned that in many cases these approaches, albeit rooted covers all aspects of the etiology, pathogenesis, diag- sis, initial treatment, and long-term management of all in available data, may be empiric rather than based varieties of thyroid cancer. Like the first edition, it will upon clear-cut results of well-controlled clinical t- als. Nevertheless, controversial issues are examined serve as a valuable reference source for pathologists, and evidence-based recommendations are presented endocrine surgeons, endocrinologists, nuclear medicine when available. physicians, and oncologists. However, the biggest There are updated chapters on our current state change is that the second edition is significantly enlarged and expanded to encompass important and extensive of knowledge of the molecular changes in thyroid treatments of more topics related to nuclear medicine. cancer, molecular markers, and how targeted the- pies are being developed.New therapeutic trials of Nuclear medicine physicians and procedures play a key redifferentiation agents to restore the sodium iodide role in the management of thyroid cancer patients and in symporter when lacking and more traditional che- retrospect, a comprehensive discussion of topics related therapies are discussed, with referral sources listed for to that field was somewhat lacking in the first edition.
Contents
Part I. General Considerations IPhysiology of the Thyroid Gland: Clinical Correlates to Thyroid Cancer Nikolaos Stathatos Epidemiology of Thyroid Cancer James J. Figge Molecular Pathogenesis of Thyroid Cancer James J. Figge, Nikolai A. Kartel, Dima Yarmolinsky, and Gennady Ermak Molecular Aspects of Thyroid Cancer in Children Gary L. Francis Oncogenes in Thyroid Cancer Katherine B. Weber and Michael T. McDermott Apoptosis in Thyroid Cancer Su He Wang and James R. Baker, Jr. Radiation-Induced Thyroid Cancer James J. Figge, Timothy Jennings, Gregory Gerasimov, Nikolai A. Kartel, Dima Yarmolinsky, and Gennady Ermak Classification of Thyroid Malignancies Yolanda C. Oertel Staging of Thyroid Cancer Leonard Wartofsky Thyroid Cancer in Children and Adolescents Merrily Poth Recombinant Human Thyrotropin Matthew D. Ringel and Stephen J. Burgun Part II. General Considerations II: Nuclear Medicine History of the Role of Nuclear Medicine in the Thyroid Gland and its Diseases: A Personal Perspective Henry N. Wagner, Jr. Prophylaxis against Radiation Exposure from Radioiodine Jacob Robbins and Arthur B. Schneider Radioiodine Whole Body Imaging Frank B. Atkins and Douglas Van Nostrand Primer and Atlas for the Interpretation of Radioiodine Whole-Body Scintigraphy Douglas Van Nostrand, Reetha Bakthula, and Frank B. Atkins False-Positive Radioiodine Scans in Thyroid Cancer Brahm Shapiro, Vittoria Rufini, Ayman Jarwan, Onelio Geatti, Kimberlee J. Kearfott, Lorraine M. Fig, Ian D. Kirkwood, John E. Freitas, and Milton D. Gross Part III. The Thyroid Nodule The Thyroid Nodule: Evaluation, Risk of Malignancy, and Management Leonard Wartofsky Fine Needle Aspiration: Technique Yolanda C. Oertel Thyroid Nodules: Cellular and Biochemical Markers for Malignancy Kathleen A. Prendergast Radionuclide Imaging of Thyroid Nodules Douglas Van Nostrand Ultrasonic Imaging of the Neck in Patients with Thyroid Cancer Manfred Blum Thyroid Nodules and Cancer Risk: Surgical Management Orlo H. Clark Part IV. Well-Differentiated Thyroid Cancer: Papillary Carcinoma A. Presentation Papillary Cancer: Clinical Aspects Leonard Wartofsky Surgical Approach to Papillary Cancer Orlo H. Clark Papillary Carcinoma: Cytology and Pathology Yolanda C. Oertel and James E. Oertel Part IV. Well-Differentiated Thyroid Cancer: B. Initial Management Prescribed Activity for Radioiodine Ablation Douglas Van Nostrand Thyroid Remnant Radioiodine Ablation with Recombinant Human Thyrotropin R. Michael Tuttle and Richard J. Robbins Part IV. Well-Differentiated Thyroid Cancer: C. Surveillance Follow-Up Strategy in Papillary Thyroid Cancer Henry B. Burch Levothyroxine Therapy and Thyrotropin Suppression Leonard Wartofsky Thyroglobulin and Thyroglobulin Antibodies: Measurement and Interferences D. Robert Dufour Diagnosis of Recurrent Thyroid Cancer in Patients with Positive Antithyroglobulin Antibodies Matthew D. Ringel Surveillance Radioiodine Whole-Body Scans Douglas Van Nostrand Radionuclide Imaging and Treatment of Thyroid Cancer in Children Gary L. Francis Positron Emission Tomography in Well-Differentiated Thyroid Cancer I. Ross McDougall Alternative Thyroid Imaging Anca M. Avram, Karen C. Rosenspire, Stewart C. Davidson, John E. Freitas, and Milton D. Gross The 'Stunning' Controversy. A. Stunning: Untoward Effect of 13
