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Full Description
The first volume to cover the entire nidovirus order, including arteriviruses, toroviruses, roniviruses, and several recently identified human coronaviruses.Provides crucial information for researchers in virology, epidemiology, biochemistry, cell biology, pathogenesis, and antiviral drug development. Synthesizes the most recent research on the basic microbiology of nidoviruses, their genetic replication, and immune system responses. Addresses the impact of the recently developed systems for nidovirus reverse genetics, the unique mechanism of nidovirus RNA synthesis, virus-host cell interactions, emerging nidovirus infections, and potential targets for therapeutic interventions. Serves as essential reading for specialists and for those interested in viral replication and pathogenesis. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Contents
Table of Contents1. An Introduction to Nidoviruses, Stuart Siddell and Eric J. Snijder2. Genomics and Evolution of Nidovirales, Alexander E. Gorbalenya3. Nidovirus Genome Organization and Expression Mechanisms, Paul Britton and Dave Cavanagh4. Genetics and Reverse Genetics of Nidoviruses, Damon J. Deming and Ralph S. Baric5. Coronavirus Replicative Proteins, John Ziebuhr6. The Arterivirus Replicase, Martin J. van Hemert and Eric J. Snijder7. Cell Biology of Nidovirus Replication Complexes, Susan C. Baker and Mark R. Denison8. RNA Signals Regulating Nidovirus RNA Synthesis, Erwin van den Born and Eric J. Snijder9. Molecular Biology and Evolution of Toroviruses, Raoul J. de Groot10. Angiotensin-Converting Enzyme 2, the Cellular Receptor for Human Coronaviruses SARS-CoV and HCoV-NL63, Wenhui Li, Hyeryhun Choe, and Michael Farzan11. Nidovirus Entry into Cells, Berend Jan Bosch and Peter J. M. Rottier12. Coronavirus Structural Proteins and Virus Assembly, Brenda G. Hogue and Carolyn E. Machamer13. Supramolecular Architecture of the Coronavirus Particle, Benjamin W. Neuman14. Arterivirus Structural Proteins and Assembly, Kay S. Faaberg15. Coronavirus Accessory Proteins, Krishna Narayanan, Cheng Huang, and Shinji Makino16. Host Cell Responses to Coronavirus Infections, Gijs A. Versteeg and Willy J. M. Spaan17. Pathogenesis of Murine Coronavirus Infection, Susan R. Weiss and Julian L. Leibowitz18. Coronaviruses of Domestic Livestock and Poultry: Interspecies Transmission, Pathogenesis, and Immunity, Linda J. Saif19. Severe Acute Respiratory Syndrome: Epidemiology, Pathogenesis, and Animal Models, John Nicholls, J. S. Malik Peiris, and Stanley Perlman20. Pathogenesis of Human Coronaviruses Other than the Severe Acute Respiratory Syndrome Virus, Pierre J. Talbot, Helene Jacomy, and Marc Desforges21. Arterivirus Pathogenesis and Immune Response, N. James MacLachlan, Udeni B. Balasuriya, Michael P. Murtaugh, Stephen W. Barthold, and Linda J. Lowenstine22. Immune Response to Coronaviruses, Cornelia C. Bergmann, Thomas E. Lane, and Stephen A. Stohlman23. Torovirus Pathogenesis and Immune Responses, Armando E. Hoet and Linda J. Saif24. Molecular Biology and Pathogenesis of Roniviruses, Jeff A. Cowley and Peter J. Walker25. Coronavirus Vaccines, with Special Focus on Severe Acute Respiratory Syndrome Virus, Luis Enjuanes, Marta L. DeDiego, Enrique Alvarez, Carmen Capiscol, and Ralph Baric26. Emerging Nidovirus Infections, Leo L. M. Poon
