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Full Description
This book has comprehensively reviewed the latest information on pyrazoles, their preparations and uses. It provides extended ideas on pyrazole and its derivatives including their synthesis, chemistry, structure activity relationship (SAR) and therapeutic applications. The health promoting properties of these pyrazoles are discussed in this book with different therapeutic applications of pyrazole scaffold. Topics related to pyrazole and its analogues as potential anticancer, anti-angiogenesis, antiviral, antioxidative, anti-convulsive, anthelmintic, anti-inflammatory, antidiabetic agents are described in this book in detail. Furthermore, current status and future prospects of pyrazole moiety in drug discovery, importance of it in plant systems, its relevance in neurological drug discovery, its potency as herbicidal and antimicrobial agents have been enumerated through different chapters. In a summary, this book is a valuable resource for research scholars, academics, students, industrialists and subject experts working in the multidisciplinary fields like medicinal chemistry, synthetic chemistry, biochemistry, pharmacology, natural product chemistry and other related areas in the field of pyrazole derivatives drug discovery and research.
Contents
Preface; Current Status of Pyrazolo Moiety in Drug Discovery (Synthetic vs. Natural); Synthesis and Therapeutic Applications of Pyrazole Scaffold; Pyrazole Based Ligands: Versatile Building Blocks; Pyrazole and Its Analogues as Potential Anti-Angiogenesis Agents; Green Chemistry Methods in Pyrazole Synthesis; Pyrazoles as Antiviral Agents; Recent Research Advances in Aqueous Phase Synthesis of Pyrazoles; Pyrazole Moiety as a Source of Natural Products; Pyrazole and Its Derivatives, Preparation, SAR and Uses as Antioxidative Agent; Role of Pyrazole Ring in Neurological Drug Discovery; Pyrano[2,3-c]pyrazole Derivatives: Synthesis and Applications; Pyrazole and Pyrazole Derivatives: A Versatile Platform in Anti-Convulsive Drug Discovery; Pyrazole Affixed Heterocycles: Synthesis and Their Herbicidal Activity; Development in Chemistry and Synthesis of Pyrazole Derivatives as Potential Anticancer Agents; Recent Advances in Chemistry and Synthesis of Pyrazole Derivatives as Potential Promising Antimicrobial Agents; Scaffold of Pyrazole Derivatives for Enzyme Inhibition; Role of Pyrazolo Ring in Plant System; Pyrazole and Its Derivatives: Preparation, SAR and Anthelmintic Activity; Pyrazole and Its Derivatives, Preparation, SAR and Anti-Inflammatory Activity; Pyrazole and Its Derivatives as Anti-Diabetic Agents; Future Prospects of Pyrazole Ring in Drug Discovery; About the Editor; Index.
