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Full Description
This book is not intended to be a basic text in infrared spectroscopy. Many such books exist and I have referred to them in the text. Rather, I have tried to find applications that would be interesting to a variety of people: advanced undergraduate chemistry students, graduate students and research workers in several disciplines, spectros copists, and physicians active in research or in the practice of medicine. With this aim in mind there was no intent to have exhaustive coverage of the literature. I should like to acknowledge my use of several books and reviews, which were invaluable in my search for material: G. H. Beaven, E. A. Johnson, H. A. Willis and R. G. 1. Miller, Molecular Spec troscopy, Heywood and Company, Ltd., London, 1961. J. A. Schell man and Charlotte Schellman, 'The Conformation of Polypeptide Chains in Proteins," in The Proteins, Vol. II, 2nd Ed. (H. Neurath, ed.), Academic Press, New York, 1964. R. T. O'Connor, "Application of Infrared Spectrophotometry to Fatty Acid Derivatives," J. Am. Oil Chemists' Soc. 33, 1 (1956). F. L. Kauffman, "Infrared Spectroscopy of Fats and Oils," J. Am. Oil Chemists' Soc. 41,4 (1964). W. J. Potts, Jr., Chemical Infrared Spectroscopy, Vol. I, Techniques, Wiley, New York, 1963. R. S. Tipson, Infrared Spectroscopy of Carbohydrates, National Bureau of Standards Monograph llO, Washington, D.C., 1968. C. N. R. Rao, Chemical Applications of Infrared Spectroscopy, Academic Press, New York, 1963.
Contents
1. Introduction and Brief Theory.- 2. Near-Infrared Spectroscopy.- 3. Sampling Methods.- 4. Quantitative Analysis.- 5. Hydrogen Bonding.- 6. Carbohydrates.- 7. Lipids.- 8. Amides.- 9. Amino Acids, Related Compounds, and Peptides.- 10. Proteins and Polypeptides.- 11. Hydrogen-Deuterium Exchange.- 12. Nucleic Acids and Related Compounds.- 13. Steroids.- 14. Porphyrins and Related Compounds.- 15. Enzymology.- 16. Drugs, Pharmaceuticals, and Pharmacological Applications.- 17. Microbiology.- 18. Applications in Medicine and Related Fields.- 19. Special Topics of Interest in Biochemistry and Related Fields.- 20. Information Sources Concerning Infrared Spectroscopy and Spectra.- Appendixes.- 1. Fractionation Methods Before the Use of Infrared Spectroscopy.- Miscellaneous Types of Chromatography (544).- Combined Use of Gas-Liquid Chromatography and Infrared Spectroscopy (548).- Ion-Exchange Chromatography (549).- Countercurrent Chromatography (549).- Molecular-Sieve Chromatography (Gel Filtration) (550).- Electrophoretic Techniques (552).- Differential Dialysis (553).- Density-Gradient Separations in the Ultra-centrifuge (553).- Countercurrent Distribution (554).- Use of the Solubility Diagram for Determining the Presence of Impurities in Soluble Materials (544).- References (554).- Additional References (558).- 2. Conversion Table—Wave Numbers and Wavelength.- General, Index.- Chemical Compound Index.
