基本説明
Covers all aspects of the metabolic syndrome and its constituent diseases, including inflammation, oxidation and adipocytokine.
Full Description
The Metabolic Syndrome is a valuable reference text, covering all aspects of the metabolic syndrome and its constituent diseases including inflammation, oxidation and adipocytokines. This book explains the aetiology, pathogenesis and clinical treatment of all risk factors as well as the relationship with diabetes, non alcoholic fatty liver disease, polycystic ovary syndrome and coronary heart disease. The Metabolic Syndrome has been further improved from the 1st edition that was highly commended in 2006 Annual British Medical Association medical books competition. All chapters from the first edition are fully updated and this new edition contains an increase in international contributions and five new chapters on:
Childhood obesity and metabolic syndrome
Bariatric surgery for obesity
Fitness
Brain insulin resistance and appetite
The nature of the insulin resistance seen in metabolic syndrome.
This brand new edition of The Metabolic Syndrome will be an indispensable resource for all clinical researchers, physicians and scientists requiring detailed up-to-date information on the metabolic syndrome to further their own research or to treat and manage the syndrome and its complications. Specifically, the text will be of particular relevance to those involved and working in the fields of diabetes, endocrinology, obesity, cardiology, vascular disease and hepatology.
Contents
List of Contributors vii
Foreword, Professor Sir George Alberti xi
Preface xiii
1 The Epidemiology of the Metabolic Syndrome and its Association with Diabetes, Cardiovascular Disease and Other Conditions 1
Sarah H. Wild and Christopher D. Byrne
2 Metabolic Syndrome and Ethnicity 19
Therese Tillin and Nita G. Forouhi
3 Developmental Origins of Endothelial Dysfunction: a Key Step in Cardiometabolic Disease 45
Christopher Torrens, Geraldine F. Clough and Mark A. Hanson
4 Developmental Origins of Insulin Resistance and Type 2 Diabetes 60
Susan E. Ozanne and Kenneth Siddle
5 The Metabolic Syndrome in Childhood 81
Ram Weiss and Sonia Caprio
6 Assessment of Insulin Sensitivity 88
Julia Szendroedi, Esther Phielix and Michael Roden
7 Recent Progress in Identifying Genes Contributing to Type 2 Diabetes and Metabolic Syndrome 106
Weijia Xie, Timothy M. Frayling and Michael N. Weedon
8 Endocrine Aspects of the Metabolic Syndrome 120
Richard I.G. Holt and Peter H. Sönksen
9 Brain Insulin Resistance 139
Katharine F. Hunt, Yee Seun Cheah and Stephanie A. Amiel
10 Cardiorespiratory Fitness and the Metabolic Syndrome 165
Paul A. McAuley and Steven N. Blair
11 Metabolic Syndrome and Mental Illness 177
Richard I.G. Holt and Robert C. Peveler
12 Atherothrombosis and the Metabolic Syndrome 194
Kristina F. Standeven and Peter J. Grant
13 Inflammation and Metabolic Syndrome 210
Sridevi Devaraj, David Siegel and Ishwarlal Jialal
14 Adipocytokine Dysregulation, Obesity and the Metabolic Syndrome 229
Ulf Smith and Xiaolin Yang
15 Non-Alcoholic Fatty Liver Disease 245
Mohamed H. Ahmed and Christopher D. Byrne
16 Polycystic Ovary Syndrome 278
Naveed Sattar
17 Nutrition: Its Relevance in Development and Treatment of the Metabolic Syndrome 297
Lisa Te Morenga and Jim Mann
18 Treatments for the Metabolic Syndrome 327
Markolf Hanefeld, Ulrike Schatz and Frank Schaper
19 Metabolic/Bariatric Surgery Therapy for the Metabolic Syndrome 347
Henry Buchwald
Index 357
