Revival: Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants (1992) (Crc Press Revivals) -- Paperback / softback

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Revival: Health Risk Assessment Dermal and Inhalation Exposure and Absorption of Toxicants (1992) (Crc Press Revivals) -- Paperback / softback

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  • 製本 Paperback:紙装版/ペーパーバック版/ページ数 544 p.
  • 言語 ENG
  • 商品コード 9781138560185
  • DDC分類 616

Full Description


Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. With contributions on topics such as PBPK modeling, cytochrome P-450 metabolism in skin, percutaneous absorption, adverse effects, new skin models, and the role of epidemiology in assessing the hazards of toxicants, Health Risk Assessment is essential for toxicologists, environmental chemists, pharmacologists, risk assessors, and managers working in industrial, pesticide, and pharmaceutical development.

Contents

Pharmacokinetics, Metabolism, And Percutaneous Penetration Of The Skin. Physiologically-Based Pharmacokinetic Modeling to Predict Tissue Dose and Cholinesterase Inhibition in Workers Exposed to Organophosphorus and Carbamate Pesticides J.B. Knaak, M.A. Al-Bayati, and O.G. Raabe The Application of Pharmacokinetic Models to Predict Target Dose Jerry N. Blancato and Kenneth B. Bischoff Cytochrome P450-Dependent Metabolism of Drugs and Carcinogens in Skin Hasan Mukhtar and Rajesh Agarwal Percutaneous Absorption Ronald C. Wester and Howard I. MaibachIn Vitro Skin Metabolism Robert L. Bronaugh and Steven W. CollierAnimal Models for Percutaneous Absorption Ronald C. Wester and Howard I. MaibachA Comparative Study of the Kinetics and Bioavailability of Pure and Soil-Absorbed Benzene, Toluene, and M-Xylene After Dermal Exposure Mohamed S. Abdel-Rahman, Gloria A. Slowronski, and Rita M. TurkallPrediction of Human Percutaneous Absorption with Physicochemical Data Robert L. Bronaugh and Curtis N. Barton Dermal Absorption of TCDD: Effect of Age Yolanda B. Banks and Linda S. Birnbaum Percutaneous Absorption of Chemicals from Water During Swimming and Bathing Ronald C. Wester and Howard I. Maibach Percutaneous Absorption of Chemicals from Soil David A.W. Bucks and Howard I. Maibach Route Of Exposure And Toxicological Response. General Overview on Toxicological Responses and Routes of Chemical Exposure Rhoda G.M. Wang Acute Toxicity Testing by the Dermal Route R.C. Myers and L.R. DePass Subchronic Dermal Exposure Studies with Industrial Chemicals David W. Hobson The Dose Response of Percutaneous Absorption Ronald C. Wester and Howard I. Maibach Reproductive and Developmental Toxicity Studies by Cutaneous Administration R. W. Tyl, R.G. York, and J.L. Schardein Dermal Carcinogenicity Studies of Petroleum-Derived Materials Richard H. McKee and James J. Freeman Comparison of Results from Carcinogenicity Tests of Two Halogenated Compounds by Oral, Dermal, and Inhalation Routes Elizabeth K. Weisburger The Objectives and Goals of Dermal Carcinogenicity Testing of Petroleum Liquids James J. Freeman and Richard H. McKee Chemical Carcinogenesis in Skin: Causation, Mechanism, and Role of Oncogenes Rajesh Agarwal and Hasan Mukhtar Dose, Toxicity, And Risk Assessment. Incorporating Biological Information into the Assessment of Cancer Risk to Humans Under Various Exposure Conditions and Issues Related to High Background Tumor Incidence RatesChao W. Chen and Kim-Chi Hoang Phototoxicity of Topical and Systemic Agents Francis N. Marzulli and Howard I. Maibach Techniques for Assessing the Health Risks of Dermal Contact with Chemicals in the EnvironmentDennis J. Paustenbach and Hon-Wing Leung Interspecies Extrapolation of Toxicological DataCurtis C. Travis New Models In Skin Research. Human Skin Xenografts to Athymic Rodents as a System to Study Toxins Delivered to or Through the Skin Gerald G. Drueger and Lynn K. Pershing The Isolated Perfused Porcine Skin Flap J.E. Riviere Epidemiologic Studies Of Route Of Exposure And Health Effects. Perspectives on Assessment of Risk from Dermal Exposure to Polycyclic Aromatic Hydrocarbons Christopher J. Borgert et al. The Paradox of Herbicide 2, 4-D Epidemiology Gregory G. Bond and Ralph R. Cook A Review of Epidemiologic Studies with Regard to Routes of Exposure to Toxicants Anthony P. Polednak

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