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Full Description
This book examines the role of pharmaceutical biotechnology in modern drug development, highlighting recent advancements in genomics, biopharmaceuticals, and personalized medicine. It explores key molecular and genomic technologies that are revolutionizing drug discovery, design, and delivery. The introductory chapters describe the essential molecular biology techniques, including next-generation sequencing and CRISPR applications, gene editing, and synthetic biology, and their role in drug discovery. Furthermore, the book explores pharmacogenomics as a link between genomics and drug response while also covering the discovery, production, and commercialization of biopharmaceuticals. It provides an in-depth discussion on the role of bioinformatics in analyzing genomic data for drug development, along with genomic strategies for target identification, validation, and the discovery of biomarkers essential to modern drug development. The book also highlights advancements in personalized medicine, emphasizing the use of genomic data to tailor treatments for individual patients. It discusses the design and therapeutic applications of monoclonal antibodies and explores breakthroughs in cell and gene therapies, addressing their potential and the challenges associated with disease treatment.
1) Provides a historical and technological perspective on pharmaceutical biotechnology and genomics.
2) Explores advanced molecular techniques, including CRISPR and next-generation sequencing, and their applications in drug discovery.
3) Discusses pharmacogenomics and the role of biomarkers in enabling personalized medicine. 4) Highlights emerging trends such as synthetic biology, gene editing, and biopharmaceutical development.
5) Addresses ethical issues and challenges in genomic research and drug development.
This book is intended for researchers and students of pharmaceutical sciences and biotechnology.
Contents
Chapter 1: Introduction to Pharmaceutical Biotechnology. Chapter 2: Fundamentals of Genomics. Chapter 3: The Human Genome Project: Impacts on Drug Development. Chapter 4: Molecular Biology Techniques in Drug Development. Chapter 5: Genomic Technologies: Next-Generation Sequencing and CRISPR Applications. Chapter 6: Emerging Biotechnologies: Gene Editing and Synthetic Biology. Chapter 7: Pharmacogenomics: Bridging Genomics and Drug Response. Chapter 8: Biopharmaceuticals from Discovery to Market. Chapter 9: Role of Bioinformatics in Analyzing Genomic Data for Drug Development. Chapter 10: Target Identification and Validation Through Genomic Approaches. Chapter 11: Biomarkers and Their Role in Modern Drug Development. Chapter 12: Personalized Medicine Using Genomic Data. Chapter 13: Design and Therapeutic Applications of Monoclonal Antibodies. Chapter 14: Advancements and Challenges in Cell and Gene Therapies for Disease Treatment. Chapter 15: Ethical Issues in Genomic Research and Drug Development. Chapter 16: Nanotechnology in Drug Delivery for Emerging Therapeutic Efficacy. Chapter 17: The Role of Artificial Intelligence in Pharmaceutical Biotechnology. Chapter 18: Future Direction in Pharmaceutical Biotechnology.
