Radiotheranostics: a Primer for Medical Physicists II : Radiochemistry, Radiobiology, Dosimetry, Safety, Economics, and AI (Series in Medical Physics and Biomedical Engineering)

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Radiotheranostics: a Primer for Medical Physicists II : Radiochemistry, Radiobiology, Dosimetry, Safety, Economics, and AI (Series in Medical Physics and Biomedical Engineering)

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  • 製本 Hardcover:ハードカバー版/ページ数 264 p.
  • 言語 ENG
  • 商品コード 9781032659701

Full Description

The book will cover all the relevant theranostics aspects involving pairs of radiopharmaceuticals used in imaging and therapy for cancer treatment: historical
perspective; cancer biology and radiation biology models; clinical applications; radionuclide production and radiopharmaceutical preparation; source calibration and imaging instrumentation; biokinetic modelling and dosimetric formalisms; epidemiological studies and clinical trials; radiation safety considerations; regulatory requirements; staff education, training and competences; economic projections, and future outlook. It is planned to keep the chapters at a medium academic level. At this time, radiotheranostics information is dispersed in books, journals, congress proceedings and organizations' websites. Compiling and organizing the material should give medical and health physicists not just the necessary tools to estimate and document the individual dosimetry of patients undergoing radiotheranostics treatment, but will also empower them to
• convince the cancer community that such a dosimetry improves cancer control and results
in longer survival times and
• influence national policy makers to require organ dose estimates/calculations.

The book is aimed at academic and practicing clinical medical and health physicists with
basic knowledge of nuclear medicine. Although the book is not meant as a textbook, medical
physicists in nuclear medicine physics training may also find the book useful.

Contents

List of Common Acronyms

Part 1 - Introduction

Chapter 1. Radiotheranostics: Challenges Today

Part 2 - Radiochemistry and Radiobiology

Chapter 2. Radiopharmaceutical Preparations and Radiolabeling Strategies

Chapter 3. New Insights Into the Radiation Biology of Radiotheranostics

Chapter 4. Radiation Embryology: Human and Animal Studies

Part 3 - Particle Dosimetry

Chapter 5. Alpha- and Beta-particle Therapy and Dosimetry

Chapter 6. Auger Emitters

Chapter 7. Positrons: Their Potential Role in Radionuclide Therapy

Part 4 - Dosimetry Formalisms

Chapter 8. Biokinetic Modelling For Radionuclide Dosimetry

Chapter 9. Standardized Tumor and Organ Dosimetry

Chapter 10. Image-based Dosimetry Procedures

Chapter 11. Combining External Beam Radiotherapy and Radionuclide Therapy

Chapter 12. Uncertainties in Dose Calculations

Part 5 - Safety

Chapter 13. Design, Shielding, and Operational Radiation Safety Aspects of the Radiotheranostic Facility

Chapter 14. Management of Deceased Patients Under Treatment (Radioactive Cadavers)

Chapter 15. Radiopharmaceutical Regulatory Requirements

Part 6 - Future Directions and Opportunities

Chapter 16. The Economics of Theranostics

Chapter 17. Artificial intelligence in Radiotheranostics

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