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Full Description
This book discusses the use of natural materials not only for the development of novel drug delivery systems applications but also for scaffold-base drug delivery used in tissue engineering. Previously biomaterials were selected primarily for their physical properties and not for delivery of active ingredients in biological systems. Natural materials containing proteins and polysaccharides are considered to be more biocompatible and less thrombogenic and
inflammatory. The novel technologies describe in this text have the unique advantage of keeping drug levels within defined ranges in a localized manner. This is accomplished while maintaining overall biocompatibility in the in vivo environment. Thus it becomes possible to increase drug efficiency and decrease
the potential for adverse reactions simultaneously, in contrast to traditional formulations that require the addition of inert materials. Such technologies are finding broad application not only in the pharmaceutical industry but also in transplantation and regeneration medicine. Scientists and engineers in industry, government, and academia who are interested in the development of novel drug delivery systems and regeneration technologies from natural materials should find this book
useful.
Contents
1. EFFICACY ASSESSMENT OF HYALURONAN VEHICLES FOR SUSTAINED RELEASE OF PDNA WEILIAM CHEN, ANGELA KIM, MARY FRAME, DANIEL CHECKLA, YANG-HYUN YUN, PAIGE YELLEN, PHILIP DEHAZYA; 3. APPLICATION OF LIPASES TO DEVELOP NOVEL ACYLTRANSFERASE SUBSTRATES THOMAS MCKEON, CHARLOTTA TURNER, SUNG-TAE KANG, XIAOHUA HE, GRACE CHEN AND JIANN-TSYH LIN; 6. SIGNIFICANT ROLE OF NATURALLY OCCURRING MATERIALS IN DRUG DELIVERY TECHNOLOGY FOR TISSUE REGENERATION THERAPY; 7. YASUHIKO TABATA; 8. ENGINEERING OF SOLID LIPID NANOPARTICLES FOR BIOMEDICAL APPLICATIONS; 9. ERIC M. SUSSMAN, ASHWATH JAYAGOPAL, FREDERIC R. HASELTON AND V. PRASAD SHASTRI; CONSTRUCTION OF MULTI-FUNCTIONAL DDS:TRANSFERRIN MEDIATED FAT AND DRUG -LOADED MAGNETIC; NANOPARTICLES JIE HUANG PENG, YAO AIJIE ZHAO, CHUNSHANG KANG, PEIYU PU, JIN CHANG; 11. A KINETIC STUDY OF POOR WATER SOLUBLE DRUG RELEASED FROM PECTIN MICROCAPSULES USING DIFFUSION/DISSOLUTION MODEL ZAYNIDDIN MUHIDINOV, JAMSHED BOBOKALONOV, LINSHU LIU, AND REZA FASSIHI; 13. ANTIBODY MODIFIED COLLAGEN MATRIX FOR SITE-SPECIFIC GENE DELIVERY XU JIN, LANXIA LIU, LIN MEI, XIGANG LENG, CHAO ZHANG, HONGFAN SUN, CUNXIAN SONG, RJ LEVY; 14. A REVIEW: CONTROLLED RELEASE SYSTEMS FOR AGRICULTURAL AND FOOD APPLICATIONS LINSHU LIU, MARSHALL F. FISHMAN AND KEVIN B. HICKS
