Full Description
Thoroughly updated for its Second Edition, this volume is the most comprehensive, current reference on perioperative transfusion medicine and coagulation. It provides complete information on all current blood products and transfusion risks, transfusion and coagulation issues during the preoperative, intraoperative, and postoperative periods, and specific concerns in each surgical subspecialty. Eighteen new chapters in this edition cover blood shortages, economic concerns, emergency needs, virus transmission, parasitic and septic risks, immunosuppression risks, non-infectious risks, production and storage issues, hemoglobin-based oxygen-carrying solutions, perfluorocarbon-based oxygen-carrying solutions, preoperative plateletphoresis, volume resuscitation, antifibrinolytics, aprotinin, DDAVP, platelet inhibitors, burn patients, and post-surgical stress response.
Contents
INTRODUCTION A History of Transfusion The Contemporary Economics of Transfusion Blood Supplies Now and in the Future Medical Ethics, Transfusion and the Standard of Practice THE PHYSIOLOGIC BASIS FOR BLOOD MANAGEMENT: A NEW LOOK Oxygen Transport Monitoring: The Basis for Developing Transfusion Triggers The Physiology of Anemia and Red Blood Cell Transfusion Physiology of Hemostasis Platelet Physiology: Cellular and Protein Interactions Iron Metabolism and Erythopoiesis New Concepts of Oxygen Transport TRANSFUSION RISKS Infectious Risks of Transfusion Immunomodulation by Transfusion Serious Acute Transfusion Reactions BLOOD COMPONENT THERAPY A Surgeon's Guide to Blood Banking and Transfusion Medicine Blood Storage Platelets Quality Control and Hospital Blood Donation Erythropoetin Therapy Hemoglobin Based Oxygen Carriers Perfluorocarbon Emulsions TRAUMA AND THE BLEEDING PATIENT Initial Resuscitation of the Hemorrhaging Patient Transfusion and Coagulation Therapy in Trauma and Burns Acute Gastrointestinal Bleeding and Transfusion Management Coagulation in Trauma: Dilution and Massive Transfusion COAGULATION ISSUES Coagulation Product Use in the Perioperative Period Coagulation Monitoring in the Perioperative Period Perioperative Management of Patients with Congenital and Acquired Clotting Deficiencies Management of Patients with Congenital Clotting Deficiencies Who Require Surgery Perioperative Management of the Hypercoagulable Patient Pharmacological Approaches to Prevent or Decrease Bleeding in Surgical Patients Fibrin Glue and Platelet Gels ANESTHESIA CONSIDERATIONS Anesthesia Techniques in Blood Conservation Perioperative Red Cell Salvage and Autotransfusion Intraoperative Acute Nomovolemic Hemodilution Hypothermia and Hemorrhage TRANSFUSION AND SURGICAL SUBSPECIALTIES Surgery in Patients with Red Cell Disorders: Sickle Hemoglobinopathies, Polycythemia, and Autoimmune Hemolytic Anemia Surgery in the Jehovah's Witness Coagulation and Transfusion Therapy in Cardiac Surgery Blood Loss and Transfusion Alternatives in Vascular Surgery Solid Organ Transplantation Blood Use in Orthopedic Obstetrics and Gynecology Hemorrhage in Pediatric Patients Transfusion in Oncologic Surgery POST-OPERATIVE TRANSFUSION ISSUES Transfusion and Outcome The Transfusion Decision Undertransfusion A Philosophy of Blood Management
