Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control

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Cutting-Edge Technology for Plant Metabolite Profiling in Drug Discovery and Quality Control

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  • 製本 Paperback:紙装版/ペーパーバック版/ページ数 450 p.
  • 言語 ENG
  • 商品コード 9780443366154

Full Description

Cutting-edge technology for plant metabolite profiling in drug discovery and quality control offers a comprehensive exploration of advanced methods in plant metabolomics and their integration with industrial applications across various sectors. The book delves into a range of methodologies, including metabolic engineering strategies, metabolite imaging techniques, nuclear magnetic resonance (NMR) for plant metabolite analysis, microfluidics for metabolite profiling, computational methods and bioinformatics tools. It also explores plant metabolomics for crop improvement, pharmaceutical development, archaeological examinations, cosmetic formulations and food quality, with case studies featured throughout the book to showcase real-world applications and scenarios. As the demand for natural products and plant-derived therapeutics continues to rise, there is a need for reliable and effective methods to identify, quantify, and optimize the bioactive compounds present in plants. This book provides a comprehensive guide to the latest advances in this field, while also delivering a multidisciplinary overview of the wide-ranging impact plant metabolites have across a variety of applications. Researchers working with plant metabolites across molecular and cellular biology, pharmaceutical science, biotechnology, biochemistry and plant science will benefit from this book. Additionally, it will be of interest to specialists working across relevant industries, such as pharmaceuticals, nutraceuticals, cosmetics and agriculture.

Contents

1. Introduction to plant metabolite profiling: Concepts and techniques
2. Metabolic engineering strategies for enhanced plant metabolite production
3. Mass spectrometry in plant metabolomics: Advances and applications
4. Nuclear magnetic resonance spectroscopy for plant metabolite analysis
5. High-performance liquid chromatography in plant metabolomics
6. Metabolite imaging techniques: From principles to applications
7. Isotope tracing and fluxomics in plant metabolism studies
8. Nuclear magnetic resonance (NMR) spectroscopy in plant metabolite analysis: Applications in drug discovery
9. Ambient ionization techniques for rapid metabolite profiling in plant-based drug development
10. Microfluidics for high-throughput plant metabolite profiling
11. Emerging trends in metabolite profiling using microfluidics and lab-on-a-chip technologies
12. Metabolomics in crop improvement: Breeding for bioactive compounds
13. Metabolite profiling of endophytic microorganisms for drug discovery
14. Quality control and standardization of herbal medicines
15. Enhancing herbal medicine quality control through advanced fingerprint analysis
16. Discovery of bioactive-chemical Q-markers for quality control of plant medicine
17. Integrative approaches of metabolomics and DNA barcoding for identifying combinatorial discriminatory quality markers
18. Combining strategy of metabolomics and transcriptomics to identify medicinal properties of plants
19. Advanced computational methods and machine learning for metabolite identification and quantification in plant-derived drugs
20. Integration of plant metabolomics with systems biology approaches
21. Data analysis and bioinformatics tools for plant metabolomics
22. Regulatory considerations in plant-derived drug development
23. A unified framework for the application of plant metabolomics advancement in industries
24. Implication of metabolomics signature in archaeological examinations
25. Environmental metabolomics: Monitoring plant responses to stressors

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