Full Description
Regulated Cell Death in Neurodegenerative Disorders is a comprehensive exploration of the mechanisms and implications of RCD within the realm of neurodegenerative diseases. The book delves into various forms of RCD such as apoptosis, necroptosis, ferroptosis, pyroptosis, and autophagy-mediated cell death, shedding light on their specific roles in disorders like Alzheimer's, Parkinson's, Multiple sclerosis, Amyotrophic lateral sclerosis, and Huntington's. Written by leading experts, each chapter offers unique insights into cellular demise, providing valuable information on treatment options and therapeutic targets. The book features 14 chapters that cover molecular, cellular, and pharmacological mechanisms from an applied science perspective.
Topics include the importance of chaperones, kinases, growth factors, inflammaging, mitochondrial dynamics, and oxidative stress. It presents targeted strategies to prevent cell death, reflecting ongoing pursuits in understanding and innovating treatments for neurodegenerative diseases. By offering therapeutic strategies to modulate RCD, this book not only shares knowledge but also provides hope for future advancements in combating these debilitating conditions.
Contents
Chapter 1. Regulated Cell Death: Discovery, Features, and Implications for Neurodegenerative Diseases
Chapter 2. Crosstalk Between Different Regulated Cell Death Mechanisms in Neurodegenerative Diseases
Chapter 3. Apoptosis in Neurodegenerative Disorders
Chapter 4. Necroptosis in Neurodegenerative Disorders
Chapter 5. Ferroptosis in Neurodegenerative Disorders
Chapter 6. Pyroptosis in Neurodegenerative Disorders
Chapter 7. Autophagy-Mediated Cell Death: Mechanisms and Implications in Neurodegenerative Disorders
Chapter 8. Potential targets for regulating cell death in neurodegenerative diseases
Chapter 9. Neuroprotective Role of Molecular Chaperones: Regulating Cell Survival and Death
Chapter 10. Navigating the Kinases Landscape: Impact on Regulated Cell Death mechanisms in Neurodegenerative disorders
Chapter 11: Growth Factors and regulated cell death in neurodegenerative disorders
Chapter 12. Regulated Cell Death and Inflammaging in Neurodegenerative Disorders
Chapter 13. Role of Oxidative Stress and Mitochondrial Dysfunction in Neurodegenerative Disorders
Chapter 14. Therapeutic Approaches Targeting Regulated Cell Death in Neurodegenerative Diseases: Current Understanding and Recent Advances in Combating Neuronal Loss
