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Full Description
Biotechnology Engineering: A Practical Approach on Bioprocess Development from Lab to Industrial Scale offers a comprehensive guide on biotechnology engineering, focusing on transforming research and development into commercially viable industrial processes. The book addresses the needs of the market by providing structured chapters, practical methods, and real-world case studies. Readers will gain valuable insights into bioprocessing basics, scalable solutions, optimization techniques, and collaboration opportunities. The text also covers essential regulatory compliance information, bridging the gap between theoretical knowledge and practical applications.
The book is a vital resource for academics, scientists, engineers, and professionals in bioprocess development. It includes detailed discussions, calculations, and case studies, modern bioreactors, and software tools used in the industry. Serving as a desktop reference, it effectively combines theory with real-world applications to support the development of bioprocesses on all scales.
Contents
PART A: Cell culture and Kinetic study
1. Culturing of microbial, animal and plant cells in lab scale
2. Microbial growth and cell kinetics
3. Design, optimization, and Inoculum development for culturing the cells
4. Lab scale studies on Submerged Liquid Fermentation (SLF) and Solid State Fermentation (SSF)
PART B: Bioreactor handling and operation
5. Fundamental of Bioreactors and accessories
6. Design Aspects and Aseptic Maintenance of Bioreactors
7. Cleaning Techniques for Bioreactors and Regulatory Standards
8. Bioreactor sterilization techniques and equipment
9. Standard Operating Procedures and Auditing in Bioprocess Industries
10. Operation and control of Submerged Liquid Fermenters
11. Operation and control of submerged solid fermenters
12. Equipment for downstream Product Recovery and Purification
13. Modern Reactors and Software Tools in Bioprocess Development
PART C: Bioreactor Scale up aspects and case studies
14. Scale-Up Rules and Reactor Accessories
15. Scale-Up Strategies for Submerged Liquid Fermentation
16. Scale-Up Strategies for Solid State Fermentation
17. Scale-Up Constraints from Lab Scale to Industrial Scale
PART D: Bioproducts
18. Commercial Bioproducts from Bioreactors
19. Bioproducts from Fermentation and their Economic Impact
20. Manufacturing Techniques for Bioproducts