Full Description
This new edition of Antifungal Therapy aims at providing concise, practical, need-to-know information for busy physicians dealing with fungal infections, such as infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. It provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment including the basics of clinical mycology, management insights for various infections, evidence-based treatment recommendations, and helpful tables summarizing currently available pharmacokinetics data.
Key Features
• Features useful information on administration, dosage and pharmacology of antifungal drugs that can be difficult to use in clinical practice
• Contains common Clinical Questions & Answers to highlight frequently encountered patient issues
• Covers clinical mycology essentials in addition to antifungal treatment to create a well-rounded reference
• Presents illustrations and clinical photos in full color to elucidate the concepts
• Provides detailed evidence of treatment recommendations
Contents
Preface
Editors
Contributors
1. History of antifungals
Emily L. Larkin, Ali Abdul Lattif Ali, and Kim Swindell
2. Epidemiology of fungal infections: What, where, and when
Frederic Lamoth, Sylvia F. Costa, and Barbara D. Alexander
3. Experimental animal models of invasive fungal infections
Christopher L. Hager, Lisa Long, Yoshifumi Imamura, and Mahmoud A. Ghannoum
4. Antifungal drug resistance: Significance and mechanisms
Sharvari Dharmaiah, Rania A. Sherif, and Pranab K. Mukherjee
5. Antifungal prophylaxis: An ounce of prevention is worth a pound of cure
Aimee K. Zaas
6. Preemptive antifungal therapy: Do diagnostics help?
Vidya Jagadeesan, Margaret Powers-Fletcher, and Kimberly E. Hanson
7. The immune response to fungal challenge
Jeffery Hu and Jeffery J. Auletta
8. Immunomodulators: What is the evidence for use in mycoses?
J. Andrew Alspaugh
9. Fungal biofilms and catheter-associated infections
Jyotsna Chandra and Mahmoud A. Ghannoum
10. Polyenes for prevention and treatment of invasive fungal infections
Richard H. Drew
11. Flucytosine
Richard H. Drew
12. Pharmacology of azole antifungal agents
Elizabeth S. Dodds Ashley
13. Echinocandins for prevention and treatment of invasive fungal infections
Melissa D. Johnson, John Mohr, and Ahmad Mourad
14. Novel methods of antifungal administration
Richard H. Drew
15. Dermatophytosis
Mahmoud A. Ghannoum, Iman Salem, and Nancy Isham
16. Invasive candidiasis
Richard R. Watkins and Tracy Lemonovich
17. Invasive aspergillosis
Frank Esper
18. Management of cryptococcosis
John R. Perfect and Ahmad Mourad
19. Management of endemic mycoses
John R. Perfect and Ahmad Mourad
20. Human hyalohyphomycoses: A review of human infections due to Acremonium spp., Paecilomyces spp., Penicillium spp., Talaromyces spp., and Scopulariopsis spp.
Nour Hasan
21. Management of phaeohyphomycosis
John R. Perfect and Ahmad Mourad
22. Pneumocystis
Kim Swindell
23. Management of mucormycoses
John R. Perfect and Ahmad Mourad
24. Antifungal management in risk groups: Solid organ transplant recipients
Jasmine Chung, Sylvia F. Costa, and Barbara D. Alexander
25. Prophylaxis and treatment of invasive fungal infections in neutropenic cancer and hematopoietic cell transplant patients
Daniel R. Richardson, Marcie L. Riches, and Hillard M. Lazarus
26. Antifungal use in transplant recipients: Selection, administration, and monitoring
Richard H. Drew, Mary L. Townsend, Melanie W. Pound, and Steven W. Johnson
27. Infants: Yeasts are beasts in early life
Rachel G. Greenberg and Daniel K. Benjamin Jr.
28. Newer antifungal agents in pediatrics
William J. Steinbach
29. Fungal infections in burn patients
Nour Hasan
30. Allergic bronchopulmonary aspergillosis
